The fertility outcome of assisted oocyte activation combined with spindle view-assisted intracytoplasmic sperm injection in patients with low fertilization rate

被引：1
作者：
Lo, Wei-Che [1 ]
Lin, Chieh-Yu [2 ]
Li, Chia-Jung [2 ]
Hou, Chiung-Hui [2 ]
Dai, Lin-Hsuan [2 ]
Wu, Hsien-Ming [1 ]
机构：
[1] Chang Gung Mem Hosp, Dept Obstet & Gynecol, 5 Fusing St, Gueishan Township 333, Taoyuan County, Taiwan
[2] Chang Gung Mem Hosp, Fertil & Reprod Genet Ctr, Taipei, Taiwan
来源：
TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY | 2024年 / 63卷 / 04期
关键词：
Assisted oocyte activation; ICSI; Polarization microscopy; Fertilization failure; Blastocyst; INFERTILE COUPLES; PLC-ZETA; FAILURE;
D O I：
10.1016/j.tjog.2023.10.017
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective: To examine the possible synergic effect of spindle view-assisted intracytoplasmic sperm injection (SV-ICSI) with assisted oocyte activation (AOA) for low fertilization rate. Materials and methods: A single-center retrospective study from 2019/09-2023/06, a total of 47 patients, autologous IVF cycle, and low fertilization rate history, including control group (SV-ICSI, 33 patients) and intervention group (AOA-SV-ICSI, 14 patients), comparing fertilization rate, blastocyst formation rate, and clinical pregnancy rate. Results: The blastocyst formation rate was significantly higher (p = 0.020) in the AOA-SV-ICSI group than in the SV-ICSI group. The fertilization rate (P = 0.468) and clinical pregnancy rate (p = 0.057) were nonsignificant between groups. Conclusion: The AOA-SV-ICSI group's blastocyst formation rate significantly improved in patients with previous low fertilization rates, which might help them obtain more useable embryos for further embryo implantation. (c) 2024 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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页码：513 / 517
页数：5
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