Investigation of Relationships between Intakes of Human Milk Total Lipids and Metabolic Hormones and Infant Sex and Body Composition

被引:1
作者
Suwaydi, Majed A. [1 ,2 ,3 ,4 ]
Lai, Ching Tat [1 ,3 ,4 ]
Warden, Ashleigh H. [1 ,3 ,4 ]
Perrella, Sharon L. [1 ,3 ,4 ]
McEachran, Jacki L. [1 ,3 ,4 ]
Wlodek, Mary E. [1 ,5 ]
Geddes, Donna T. [1 ,3 ,4 ]
Gridneva, Zoya [1 ,3 ,4 ]
机构
[1] Univ Western Australia, Sch Mol Sci, Crawley, WA 6009, Australia
[2] Jazan Univ, Sch Appl Med Sci, Jazan 45142, Saudi Arabia
[3] ABREAST Network, Perth, WA 6000, Australia
[4] UWA Ctr Human Lactat Res & Translat, Crawley, WA 6009, Australia
[5] Univ Melbourne, Dept Obstet Gynaecol & Newborn Hlth, Parkville, Vic 3010, Australia
关键词
human milk; lactation; leptin; adiponectin; insulin; total lipids; intake; body composition; infant; adiposity; BREAST-MILK; MOTHERS MILK; HUMAN LACTATION; MATERNAL SERUM; LEPTIN LEVELS; WEIGHT-GAIN; FAT-CONTENT; 1ST YEAR; ADIPONECTIN; ENERGY;
D O I
10.3390/nu16162739
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Human milk (HM) composition, including metabolic hormones and lipids, is influenced by various factors, including lactation stage and, potentially, infant sex, which may affect infant body composition (BC) development. We aimed to: (a) characterize the longitudinal concentration and intake profiles of HM leptin, adiponectin, insulin, and total lipids; (b) determine if their concentrations and intakes differ by infant sex; and (c) explore the intakes relationships with the development of infant BC. Milk samples (n = 501) were collected from 82 mother-infant dyads during the first 6 months postpartum. Infant 24 h HM intake was measured, and the average cumulative HM component intakes were calculated. The statistical analysis used linear mixed modeling. Intakes of HM leptin, adiponectin, insulin, and total lipids increased to 1 month postpartum and then remained stable. HM intake and total lipids intake but not hormone intakes were positively associated with infant BC (fat-free mass, fat-free mass index, fat mass, fat mass index, percentage fat mass, and fat mass to fat-free mass ratio). HM component concentrations and intakes did not differ by sex. These findings advance our understanding of the temporal nature of HM components, emphasizing the role of infant 24 h HM and total lipids intake in development of infant lean and adipose tissue.
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页数:21
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共 102 条
  • [1] Impact of maternal BMI and sampling strategy on the concentration of leptin, insulin, ghrelin and resistin in breast milk across a single feed: a longitudinal cohort study
    Andreas, Nicholas J.
    Hyde, Matthew J.
    Herbert, Bronwen R.
    Jeffries, Suzan
    Santhakumaran, Shalini
    Mandalia, Sundhiya
    Holmes, Elaine
    Modi, Neena
    [J]. BMJ OPEN, 2016, 6 (07):
  • [2] Effect of Maternal Body Mass Index on Hormones in Breast Milk: A Systematic Review
    Andreas, Nicholas J.
    Hyde, Matthew J.
    Gale, Chris
    Parkinson, James R. C.
    Jeffries, Suzan
    Holmes, Elaine
    Modi, Neena
    [J]. PLOS ONE, 2014, 9 (12):
  • [3] Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
    Arita, Y
    Kihara, S
    Ouchi, N
    Takahashi, M
    Maeda, K
    Miyagawa, J
    Hotta, K
    Shimomura, I
    Nakamura, T
    Miyaoka, K
    Kuriyama, H
    Nishida, M
    Yamashita, S
    Okubo, K
    Matsubara, K
    Muraguchi, M
    Ohmoto, Y
    Funahashi, T
    Matsuzawa, Y
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1999, 257 (01) : 79 - 83
  • [4] MEASUREMENT OF THE MILK INTAKE OF BREAST-FED INFANTS
    ARTHUR, PG
    HARTMANN, PE
    SMITH, M
    [J]. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 1987, 6 (05) : 758 - 763
  • [5] Human Milk Composition Nutrients and Bioactive Factors
    Ballard, Olivia
    Morrow, Ardythe L.
    [J]. PEDIATRIC CLINICS OF NORTH AMERICA, 2013, 60 (01) : 49 - +
  • [6] Fitting Linear Mixed-Effects Models Using lme4
    Bates, Douglas
    Maechler, Martin
    Bolker, Benjamin M.
    Walker, Steven C.
    [J]. JOURNAL OF STATISTICAL SOFTWARE, 2015, 67 (01): : 1 - 48
  • [7] Time-course of leptin levels in term and preterm human milk
    Bielicki, J
    Huch, R
    von Mandach, U
    [J]. EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2004, 151 (02) : 271 - 276
  • [8] Boss Melinda, 2018, F1000Res, V7, DOI 10.12688/f1000research.14452.1
  • [9] Adiponectin, AFABP, and Leptin in Human Breast Milk During 12 Months of Lactation
    Bronsky, Jiri
    Mitrova, Katarina
    Karpisek, Michal
    Mazoch, Jiri
    Durilova, Marianna
    Fisarkova, Barbora
    Stechova, Katerina
    Prusa, Richard
    Nevoral, Jiri
    [J]. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2011, 52 (04) : 474 - 477
  • [10] Body composition during the first 2 years of life: An updated reference
    Butte, NF
    Hopkinson, JM
    Wong, WW
    Smith, EO
    Ellis, KJ
    [J]. PEDIATRIC RESEARCH, 2000, 47 (05) : 578 - 585