Engineering multifunctional GRP78-CAR CIK cells to target relapsed/refractory pediatric AML

被引：0

作者：

Hopke, E. ^{[1
]}

Bhayadia, R. ^{[1
]}

Moser, L. ^{[1
]}

Prufer, M. ^{[2
]}

Laszig, S. ^{[1
]}

Soldierer, M. ^{[3
]}

Issa, H. ^{[1
]}

Wels, W. S. ^{[2
]}

Klusmann, J. H. ^{[1
]}

Rettinger, E. ^{[1
]}

机构：

[1] Goethe Univ Frankfurt, Univ Hosp, Dept Children & Adolescents, Frankfurt, Germany

[2] Inst Tumor Biol & Expt Therapy, Georg Speyer Haus, Frankfurt, Germany

[3] Univ Duisburg Essen, Univ Childrens Hosp Essen, Dept Pediat 3, Essen, Germany

来源：

KLINISCHE PADIATRIE | 2024年 / 236卷 / 03期

关键词：

D O I：

10.1055/s-0044-1786591

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

0040

引用

页码：208 / 208

页数：1

共 27 条

[1] GRP78 Is Expressed on the Cell Surface of Pediatric AML Blasts and Can be Targeted with GRP78-CAR T Cells without Toxicity to Hematopoietic Progenitor Cells
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[2] GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells
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CELL REPORTS MEDICINE, 2023, 4 (11)
[3] Treating Relapsed / Refractory (RR) AML with Biodegradable Anti-CD123 CAR Modified T Cells
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[4] Low-dose daunorubicin to target leukemia stem cells in newly diagnosed and relapsed/refractory AML
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[5] DNT cells mediate resistance to CAR-T cells therapy in a pediatric patient with relapsed and refractory B-ALL
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[6] CAR T cells redirected to cell surface GRP78 display robust anti-acute myeloid leukemia activity and do not target hematopoietic progenitor cells
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[7] CAR T cells redirected to cell surface GRP78 display robust anti-acute myeloid leukemia activity and do not target hematopoietic progenitor cells
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[8] Engineering tandem CD33xCD146 CAR CIK (cytokine-induced killer) cells to target the acute myeloid leukemia niche
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[10] Humanized CD19-targeted chimeric antigen receptor T (CAR-T) cells for relapsed/refractory pediatric acute lymphoblastic leukemia
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