Dual-etiology MAFLD: the interactions between viral hepatitis B, viral hepatitis C, alcohol, and MAFLD

被引：6

作者：

Liu, Chun-Jen ^{[1
,2
,3
,4
]}

Seto, Wai Kay ^{[5
]}

Yu, Ming-Lung ^{[6
,7
,8
,9
,10
]}

机构：

[1] Natl Taiwan Univ, Coll Med, Hepatitis Res Ctr, Taipei, Taiwan

[2] Natl Taiwan Univ Hosp, Taipei, Taiwan

[3] Natl Taiwan Univ, Grad Inst Clin Med, Coll Med, Taipei, Taiwan

[4] Natl Taiwan Univ, Dept Internal Med, Div Gastroenterol & Hepatol, Coll Med, Taipei, Taiwan

[5] Univ Hong Kong, Sch Clin Med, Dept Med, Pok Fu Lam, Hong Kong, Peoples R China

[6] Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Coll Med, Ctr Hepatitis Res,Hepatobiliary Div,Dept Internal, Kaohsiung, Taiwan

[7] Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Ctr Liquid Biopsy & Cohort Res, Kaohsiung, Taiwan

[8] Natl Sun Yat Sen Univ, Coll Med, Sch Med, Kaohsiung, Taiwan

[9] Natl Sun Yat Sen Univ, Coll Med, Doctoral Program Clin & Expt Med, Kaohsiung, Taiwan

[10] Natl Sun Yat Sen Univ, Ctr Excellence Metab Associated Fatty Liver Dis, Kaohsiung, Taiwan

来源：

HEPATOLOGY INTERNATIONAL | 2024年 / 18卷 / SUPPL 2期

关键词：

Steatosis; Hepatitis B virus; Hepatitis C virus; Fatty liver; Steatohepatitis; Alcoholic liver disease; FATTY LIVER-DISEASE; CONTROLLED ATTENUATION PARAMETER; METABOLIC RISK-FACTORS; BODY-MASS INDEX; HEPATOCELLULAR-CARCINOMA; VIRUS INFECTION; INSULIN-RESISTANCE; STEATOSIS; ASSOCIATION; FIBROSIS;

D O I：

10.1007/s12072-024-10699-x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Metabolic dysfunction-associated fatty liver disease (MAFLD) and viral hepatitis due to chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection are common liver diseases worldwide. Excessive alcohol consumption and alcoholic liver disease (ALD) are also emerging health problems. Therefore, in clinical practice, we may encounter subjects with dual etiology of liver diseases such as coexisting MAFLD/HBV, MAFLD/HCV, and MAFLD/ALD. In this review, we summarize the epidemiology, clinical features, and mutual interactions of MAFLD with coexisting HBV, HCV, or ALD. The impact of MAFLD on the progression of liver diseases and treatment outcomes in patients with chronic viral hepatitis and the clinical questions to be addressed regarding dual MAFLD and ALD are also discussed.

引用

页码：897 / 908

页数：12

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