Sarcoidosis: When the diagnosis is not what it seems

被引:0
作者
de Albuquerque-Monteiro, Ines [1 ]
Silverio, Bernardo [1 ]
Freitas, Isabel [1 ]
Teixeira, Sofia [1 ]
机构
[1] Ctr Hosp Medio Ave, Vila Nova De Famalicao, Portugal
来源
GALICIA CLINICA | 2024年 / 85卷 / 02期
关键词
Sarcoidosis; non-caseating granulomas; adenopathy; lymphoproliferative;
D O I
10.22546/73/4129
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Sarcoidosis is a multisystemic disease characterized by the presence of non-caseating granulomas. We present a 26-year-old man who presents to the emergency department with fever, myalgia, excessive sweating, and weight loss. The analysis reveals pancytopenia, high than 150 U/L; splenomegaly, peri-aortic-caval retroperitoneal adenopathies confirmed by imaging. After ruling out the most common causes, a bronchoalveolar lavage showed an elevated CD4/CD8 ratio and lymphocytosis exceeding 50%, as well as confluent non-caseating epithelioid granulomas in the biopsy of the adenopathy, establishing the diagnosis of stage III sarcoidosis.
引用
收藏
页码:37 / 39
页数:3
相关论文
共 6 条
[1]   Sarcoidosis: a review for the internist [J].
Bargagli, Elena ;
Prasse, Antje .
INTERNAL AND EMERGENCY MEDICINE, 2018, 13 (03) :325-331
[2]  
Castelo Branco S, 2015, Revista da Sociedade Portuguesa de Dermatologia e Venereologia, V74
[3]   Challenges of Sarcoidosis and Its Management [J].
Drent, Marjolein ;
Crouser, Elliott D. ;
Grunewald, Johan .
NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (11) :1018-1032
[4]   Challenging Mimickers in the Diagnosis of Sarcoidosis: A Case Study [J].
El Jammal, Thomas ;
Jamilloux, Yvan ;
Gerfaud-Valentin, Mathieu ;
Richard-Colmant, Gaelle ;
Weber, Emmanuelle ;
Bert, Arthur ;
Androdias, Geraldine ;
Seve, Pascal .
DIAGNOSTICS, 2021, 11 (07)
[5]   Diagnosis issues in sarcoidosis [J].
Jeny, F. ;
Bernaudin, J. -F. ;
Aubart, F. Cohen ;
Brillet, P. -Y. ;
Bouvry, D. ;
Nunes, H. ;
Valeyre, D. .
RESPIRATORY MEDICINE AND RESEARCH, 2020, 77 :37-45
[6]   Sarcoidosis: A Clinical Overview from Symptoms to Diagnosis [J].
Seve, Pascal ;
Pacheco, Yves ;
Durupt, Francois ;
Jamilloux, Yvan ;
Gerfaud-Valentin, Mathieu ;
Isaac, Sylvie ;
Boussel, Loic ;
Calender, Alain ;
Androdias, Geraldine ;
Valeyre, Dominique ;
El Jammal, Thomas .
CELLS, 2021, 10 (04)