Large-Scale Serological Survey of Crimean-Congo Hemorrhagic Fever Virus and Rift Valley Fever Virus in Small Ruminants in Senegal

被引：1

作者：

Gahn, Marie Cicille Ba ^{[1
]}

Diouf, Gorgui ^{[1
]}

Cisse, Ndjibouye ^{[1
]}

Ciss, Mamadou ^{[1
]}

Bordier, Marion ^{[1
,2
]}

Ndiaye, Mbengue ^{[1
]}

Bakhoum, Mame Thierno ^{[1
]}

Djiba, Mamadou Lamine ^{[1
]}

Brown, Corrie ^{[3
]}

Faburay, Bonto ^{[4
]}

Fall, Assane Gueye ^{[1
]}

Lo, Modou Moustapha ^{[1
]}

机构：

[1] Lab Natl Elevage & Rech Veterinaires ISRA LNERV, Inst Senegalais Rech Agr, BP 2057, Dakar, Senegal

[2] UMR ASTRE, Ctr Cooperat Internatl Rech Agron Dev CIRAD, F-34398 Montpellier, France

[3] LifeStock Int, 550 Fortson Rd, Athens, GA 30606 USA

[4] united States Dept Agr, Natl Vet Serv Labs, Foreign Anim Dis Diagnost Lab, Natl Bio & Agrodef Facil, Manhattan, KS 66505 USA

来源：

PATHOGENS | 2024年 / 13卷 / 08期

基金：

美国农业部;

关键词：

Crimean-Congo hemorrhagic fever; Rift Valley fever; serological survey; small-ruminant; Senegal; SEROPREVALENCE; PREVALENCE; INFECTION; VECTORS;

D O I：

10.3390/pathogens13080689

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Crimean-Congo hemorrhagic fever (CCHF) and Rift Valley fever (RVF) are among the list of emerging zoonotic diseases that require special attention and priority. RVF is one of the six priority diseases selected by the Senegalese government. Repeated epidemic episodes and sporadic cases of CCHF and RVF in Senegal motivated this study, involving a national cross-sectional serological survey to assess the distribution of the two diseases in this country throughout the small ruminant population. A total of 2127 sera from small ruminants (goat and sheep) were collected in all regions of Senegal. The overall seroprevalence of CCHF and RVF was 14.1% (IC 95%: 12.5-15.5) and 4.4% (95% CI: 3.5-5.3), respectively. The regions of Saint-Louis (38.4%; 95% CI: 30.4-46.2), Kolda (28.3%; 95% CI: 20.9-35.7), Tambacounda (22.2%; 95% CI: 15.8-28.6) and K & eacute;dougou (20.9%; 95% CI: 14.4-27.4) were the most affected areas. The risk factors identified during this study show that the age, species and sex of the animals are key factors in determining exposure to these two viruses. This study confirms the active circulation of CCHF in Senegal and provides important and consistent data that can be used to improve the surveillance strategy of a two-in-one health approach to zoonoses.

引用

页数：11