Sc(OTf)3-Catalyzed Synthesis of 3-Substituted Lawsones through a Buchner-Curtius-Schlotterbeck Reaction

被引：0

作者：

Gogula, Sailam Sri ^{[1
,2
]}

Prasanna, Dasari Vijaya ^{[2
]}

Sridhar, B. ^{[3
]}

Lincoln, Ch. Abraham ^{[1
]}

Reddy, P. Muralidhar ^{[1
]}

Reddy, B. V. Subba ^{[2
]}

机构：

[1] Osmania Univ, Dept Chem, Hyderabad 500007, India

[2] CSIR Indian Inst Chem Technol, Fluoro Agrochem, Hyderabad 500007, India

[3] CSIR Indian Inst Chem Technol, Lab Xray Crystallog, Hyderabad 500007, India

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 27卷 / 31期

关键词：

Diazo compounds; ninhydrin; 3-substituted lawsones; Scandium triflate; C-H insertion reactions; NAPHTHOQUINONE DERIVATIVES; ARYLATION; CYCLOALKANONES; EFFICIENT; INSERTION;

D O I：

10.1002/ejoc.202400362

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient strategy has been developed for the synthesis of 3-substituted lawsones using a catalytic amount of Sc(OTf)(3) in toluene at -78 degrees C through a Buchner-Curtius-Schlotterbeck reaction. It is a versatile method to produce a large number of 3-aryl, 3-styryl, 3-alkyl, and 3-heteroaryl substituted lawsones under mild conditions. This is a first report on the synthesis of 3-substituted lawsones in high yields with in short reaction times.

引用

页数：4

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