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Exploring the Therapeutic Potential of Tyrosol and Its Derivatives: A Comprehensive Review
被引:0
|作者:
Raj, D. K. Gokul
[1
]
Milan, K. L.
[1
]
Ramkumar, Kunka Mohanram
[1
]
机构:
[1] SRM Inst Sci & Technol, Sch Bioengn, Dept Biotechnol, Kattankulathur 603203, Tamil Nadu, India
关键词:
Tyrosol;
pharmacokinetics;
pharmacology;
diseases;
diabetes;
cardiovascular disease;
neuroprotection;
anti-inflammatory;
OIL PHENOLIC-COMPOUNDS;
VIRGIN OLIVE OIL;
GLOBAL CEREBRAL-ISCHEMIA;
ACUTE LUNG INJURY;
NF-KAPPA-B;
IN-VITRO;
P-TYROSOL;
ANTIOXIDANT ACTIVITY;
CHEMICAL-CHARACTERIZATION;
COMPOUNDS INHIBIT;
D O I:
10.2174/0109298673330437240816150736
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
Tyrosol (Ty) and its derivatives have gathered considerable attention in recent years due to their diverse pharmacological properties and potential therapeutic applications. This comprehensive review aims to summarize the current understanding of the therapeutic potential of Ty and its derivatives in combating various diseases, including cancer, cardiovascular disease (CVD), neurodegenerative diseases, diabetes, and obesity. This review highlights the multifaceted properties of Ty, including its pharmacokinetic profile and pharmacological actions, which contribute to its efficacy against these prevalent health conditions. Moreover, the antimicrobial and wound-healing effects of Ty are explored, elucidating its potential for broader therapeutic utilization. While existing studies provide evidence supporting the beneficial effects of Ty, gaps remain in our understanding of its molecular mechanisms of action and the exploration of novel derivatives. Future research efforts are thus critical for unraveling the full therapeutic potential of Ty and its derivatives. Moreover, the synthesis of novel derivatives with enhanced efficacy and improved bioavailability shows potential for addressing unmet medical needs. This review emphasizes the necessity for ongoing research into Ty and its derivatives, providing valuable insights into their potential as essential therapeutic agents for addressing diverse health conditions.
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页数:22
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