Biochemical assessment of amniotic membrane extract for optimal application in regenerative medicine

被引：1

作者：

Bedewy, Nourhan ^{[1
]}

Elbordiny, Magdy ^{[1
]}

Swelem, Manal ^{[2
]}

Eldabah, Nermeen ^{[1
]}

机构：

[1] Alexandria Univ, Dept Clin & Chem Pathol, Alexandria, Egypt

[2] Alexandria Univ, Dept Obstet & Gynecol, Alexandria, Egypt

来源：

ALEXANDRIA JOURNAL OF MEDICINE | 2024年 / 60卷 / 01期

关键词：

Amniotic membrane; subregional variances; regenerative medicine; GROWTH-FACTOR; BETA;

D O I：

10.1080/20905068.2024.2380213

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

ObjectiveAmniotic membrane (AM) extract is a promising tool in regenerative medicine, which offers similar therapeutic effects as intact AM but with a simpler and safer approach. AM displays several subregional variances.MethodThe quantitative analysis of hepatocyte growth factor (HGF) and transforming growth factor-beta 1 (TGF-beta 1) in placental and reflected AM sections were assayed by enzyme-linked immunosorbent assay.ResultsDetection of high levels of HGF and TGF-beta 1 with variation in concentration between the placental and reflected portions of the same membrane.ConclusionUnderstanding AM subregional variations would optimize AM extract preparation for specific regenerative medicine therapies.

引用

页码：215 / 221

页数：7

共 36 条

[31]

Sherbet GV, 2011, GROWTH FACTORS AND THEIR RECEPTORS IN CELL DIFFERENTIATION, CANCER AND CANCER THERAPY, P65, DOI 10.1016/B978-0-12-387819-9.00005-0

[32]

Shimmura Shigeto, 2002, Curr Opin Ophthalmol, V13, P213, DOI 10.1097/00055735-200208000-00004

[33] Protective effect of human amniotic membrane extract against hydrogen peroxide-induced oxidative damage in human dermal fibroblasts [J].

Talachi, Negin ;

Afzal, Elaheh ;

Nouri, Masoumeh ;

Abroun, Saeid ;

Zarrabi, Morteza ;

Jahandar, Hoda .

INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, 2023, 45 (01) :73-82

[34]

Tseng Scheffer C G, 2004, Ocul Surf, V2, P177

[35] Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis [J].

Walton, Kelly L. ;

Johnson, Katharine E. ;

Harrison, Craig A. .

FRONTIERS IN PHARMACOLOGY, 2017, 8

[36] Sub-Regional Differences of the Human Amniotic Membrane and Their Potential Impact on Tissue Regeneration Application [J].

Weidinger, Adelheid ;

Pozenel, Laura ;

Wolbank, Susanne ;

Banerjee, Asmita .

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2021, 8

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