Biochemical assessment of amniotic membrane extract for optimal application in regenerative medicine

被引：1

作者：

Bedewy, Nourhan ^{[1
]}

Elbordiny, Magdy ^{[1
]}

Swelem, Manal ^{[2
]}

Eldabah, Nermeen ^{[1
]}

机构：

[1] Alexandria Univ, Dept Clin & Chem Pathol, Alexandria, Egypt

[2] Alexandria Univ, Dept Obstet & Gynecol, Alexandria, Egypt

来源：

ALEXANDRIA JOURNAL OF MEDICINE | 2024年 / 60卷 / 01期

关键词：

Amniotic membrane; subregional variances; regenerative medicine; GROWTH-FACTOR; BETA;

D O I：

10.1080/20905068.2024.2380213

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

ObjectiveAmniotic membrane (AM) extract is a promising tool in regenerative medicine, which offers similar therapeutic effects as intact AM but with a simpler and safer approach. AM displays several subregional variances.MethodThe quantitative analysis of hepatocyte growth factor (HGF) and transforming growth factor-beta 1 (TGF-beta 1) in placental and reflected AM sections were assayed by enzyme-linked immunosorbent assay.ResultsDetection of high levels of HGF and TGF-beta 1 with variation in concentration between the placental and reflected portions of the same membrane.ConclusionUnderstanding AM subregional variations would optimize AM extract preparation for specific regenerative medicine therapies.

引用

页码：215 / 221

页数：7

共 36 条

[21] TGF-β1-A truly transforming growth factor in fibrosis and immunity [J].

Lodyga, Monika ;

Hinz, Boris .

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2020, 101 :123-139

[22]

Lopez CFV., 2024, Academic Med Surg, DOI [10.62186/001c.92290, DOI 10.62186/001C.92290]

[23]

Mahbod Mirgholamreza, 2014, J Ophthalmic Vis Res, V9, P314, DOI 10.4103/2008-322X.143367

[24] Agent-based model of inflammation and wound healing:: insights into diabetic foot ulcer pathology and the role of transforming growth factor-β1 [J].

Mi, Qi ;

Riviere, Beatrice ;

Clermont, Gilles ;

Steed, David L. ;

Vodovotz, Yoram .

WOUND REPAIR AND REGENERATION, 2007, 15 (05) :671-682

[25]

NAKAMURA T, 1994, MOLECULAR AND CELLULAR BASIS FOR CELL TO CELL INTERACTION: ITS SIGNIFICANCE IN CANCER, P195

[26] Hepatocyte growth factor twenty years on: Much more than a growth factor [J].

Nakamura, Takahiro ;

Sakai, Katsuya ;

Nakamura, Toshikazu ;

Matsumoto, Kunio .

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2011, 26 :188-202

[27]

Nickerson B, 2011, SAMPLE PREPARATION OF PHARMACEUTICAL DOSAGE FORMS: CHALLENGES AND STRATEGIES FOR SAMPLE PREPARATION AND EXTRACTION, P43, DOI 10.1007/978-1-4419-9631-2_3

[28] Critical Role of Transforming Growth Factor Beta in Different Phases of Wound Healing [J].

Pakyari, Mohammadreza ;

Farrokhi, Ali ;

Maharlooei, Mohsen Khosravi ;

Ghahary, Aziz .

ADVANCES IN WOUND CARE, 2013, 2 (05) :215-224

[29] The Antibacterial Activity of Human Amniotic Membrane against Multidrug-Resistant Bacteria Associated with Urinary Tract Infections: New Insights from Normal and Cancerous Urothelial Models [J].

Ramuta, Taja Zeleznik ;

Tratnjek, Larisa ;

Janev, Aleksandar ;

Seme, Katja ;

Erjavec, Marjanca Starcic ;

Kreft, Mateja Erdani .

BIOMEDICINES, 2021, 9 (02) :1-22

[30]

Rodella A., 2019, Wound Med., V27, DOI DOI 10.1016/J.WNDM.2019.100171

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