Biochemical assessment of amniotic membrane extract for optimal application in regenerative medicine

被引：1
作者：
Bedewy, Nourhan [1 ]
Elbordiny, Magdy [1 ]
Swelem, Manal [2 ]
Eldabah, Nermeen [1 ]
机构：
[1] Alexandria Univ, Dept Clin & Chem Pathol, Alexandria, Egypt
[2] Alexandria Univ, Dept Obstet & Gynecol, Alexandria, Egypt
来源：
ALEXANDRIA JOURNAL OF MEDICINE | 2024年 / 60卷 / 01期
关键词：
Amniotic membrane; subregional variances; regenerative medicine; GROWTH-FACTOR; BETA;
D O I：
10.1080/20905068.2024.2380213
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
ObjectiveAmniotic membrane (AM) extract is a promising tool in regenerative medicine, which offers similar therapeutic effects as intact AM but with a simpler and safer approach. AM displays several subregional variances.MethodThe quantitative analysis of hepatocyte growth factor (HGF) and transforming growth factor-beta 1 (TGF-beta 1) in placental and reflected AM sections were assayed by enzyme-linked immunosorbent assay.ResultsDetection of high levels of HGF and TGF-beta 1 with variation in concentration between the placental and reflected portions of the same membrane.ConclusionUnderstanding AM subregional variations would optimize AM extract preparation for specific regenerative medicine therapies.
引用
收藏
页码：215 / 221
页数：7
相关论文
共 36 条
[1]  
Alamouti MA., 2019, IRAN J DIAB LIPID DI, V18, P126
[2]   Scarring impedes regeneration at sites of peripheral nerve repair [J].
Atkins, Simon ;
Smith, Keith G. ;
Loescher, Alison R. ;
Boissonade, Fiona M. ;
O'Kane, Sharon ;
Ferguson, Mark W. J. ;
Robinson, Peter P. .
NEUROREPORT, 2006, 17 (12) :1245-1249
[3]   Oxygen Tension Strongly Influences Metabolic Parameters and the Release of Interleukin-6 of Human Amniotic Mesenchymal Stromal Cells In Vitro [J].
Banerjee, Asmita ;
Lindenmair, Andrea ;
Steinborn, Ralf ;
Dumitrescu, Sergiu Dan ;
Hennerbichler, Simone ;
Kozlov, Andrey, V ;
Redl, Heinz ;
Wolbank, Susanne ;
Weidinger, Adelheid .
STEM CELLS INTERNATIONAL, 2018, 2018
[4]   Mapping of the Human Placenta: Experimental Evidence of Amniotic Epithelial Cell Heterogeneity [J].
Centurione, Lucia ;
Passaretta, Francesca ;
Centurione, Maria Antonietta ;
De Munari, Silvia ;
Vertua, Elsa ;
Silini, Antonietta ;
Liberati, Marco ;
Parolini, Ornella ;
Di Pietro, Roberta .
CELL TRANSPLANTATION, 2018, 27 (01) :12-22
[5]   Amniotic membrane extract-loaded double-layered wound dressing: evaluation of gel properties and wound healing [J].
Choi, Yeung Keun ;
Din, Fakhar Ud ;
Kim, Dong Wuk ;
Kim, Yong-Il ;
Kim, Jong Oh ;
Ku, Sae Kwang ;
Ra, Jeong-Chan ;
Huh, Jae-Wook ;
Lee, Jangik I. ;
Sohn, Dong Hwan ;
Yong, Chul Soon ;
Choi, Han-Gon .
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2014, 40 (07) :852-859
[6]  
Costa E., 2015, Amniotic membrane: origin, characterization and medical applications, V1st, P105, DOI [DOI 10.1007/978-94-017-9975-1, 10.1007/978-94-017-9975-1_6]
[7]   A Review on Modifications of Amniotic Membrane for Biomedical Applications [J].
Dadkhah Tehrani, Fatemeh ;
Firouzeh, Arezoo ;
Shabani, Iman ;
Shabani, Azadeh .
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2021, 8
[8]   Effects of amniotic membrane extract on primary human corneal epithelial and limbal cells [J].
Dudok, David V. ;
Nagdee, Imraan ;
Cheung, Kevin ;
Liu, Hong ;
Vedovelli, Luca ;
Ghinelli, Emiliano ;
Kenyon, Kenneth ;
Parapuram, Sunil ;
Hutnik, Cindy M. .
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2015, 43 (05) :443-448
[9]   Applications of the amniotic membrane in tissue engineering and regeneration: the hundred-year challenge [J].
Elkhenany, Hoda ;
El-Derby, Azza ;
Abd Elkodous, Mohamed ;
Salah, Radwa A. ;
Lotfy, Ahmed ;
El-Badri, Nagwa .
STEM CELL RESEARCH & THERAPY, 2022, 13 (01)
[10]  
Emge LA., 1921, Anatomical Rec, V22, P342, DOI [10.1002/ar.1090220507, DOI 10.1002/AR.1090220507]
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