A Case of Pernicious Anemia with Concurrent Beta-Thalassemia Minor

被引:0
作者
Yuan, Fuzhen [1 ]
Huang, Zhenhua [1 ,2 ]
Yao, Dingye [1 ,2 ]
Sun, Junsheng [1 ,2 ]
机构
[1] Longgang Dist Cent Hosp Shenzhen, Dept Gen Practice, Shenzhen 5181116, Peoples R China
[2] Guangzhou Univ Chinese Med, Shenzhen Clin Coll Med, Shenzhen 5181116, Peoples R China
来源
JOURNAL OF BLOOD MEDICINE | 2024年 / 15卷
关键词
pernicious anemia; autoimmune gastritis; thalassemia; glossitis;
D O I
10.2147/JBM.S473075
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Vitamin B12 is essential for various bodily functions, and its deficiency may cause hematological manifestations. We report a case of a previously healthy 65-year-old female who was admitted to our hospital with reduced sense of taste and painful tongue. The serum level of vitamin B12 was decreased. However, her complete blood count did not show any evidence of macrocytosis, instead, her mean corpuscular volume was low. Gene sequencing indicated an beta-thalassemia minor and that probably masked the megaloblastic features of vitamin B12 deficiency.
引用
收藏
页码:351 / 357
页数:7
相关论文
共 10 条
  • [1] Grave and Pernicious Anemia Presenting as Pancytopenia
    Groth, Alexandra
    Rudiger, Alain
    Herren, Thomas
    [J]. AMERICAN JOURNAL OF MEDICINE, 2020, 133 (06) : E302 - E303
  • [2] Chronic atrophic gastritis: Natural history, diagnosis and therapeutic management. A position paper by the Italian Society of Hospital Gastroenterologists and Digestive Endoscopists [AIGO], the Italian Society of Digestive Endoscopy [SIED], the Italian Society of Gastroenterology [SIGE], and the Italian Society of Internal Medicine [SIMI]
    Lahner, Edith
    Zagari, Rocco Maurizio
    Zullo, Angelo
    Di Sabatino, Antonio
    Meggio, Alberto
    Cesaro, Paola
    Lenti, Marco Vincenzo
    Annibale, Bruno
    Corazza, Gino Roberto
    [J]. DIGESTIVE AND LIVER DISEASE, 2019, 51 (12) : 1621 - 1632
  • [3] The prevalence of thalassemia in mainland China: evidence from epidemiological surveys
    Lai, Ketong
    Huang, Guifeng
    Su, Li
    He, Yunyan
    [J]. SCIENTIFIC REPORTS, 2017, 7
  • [4] Autoimmune gastritis
    Lenti, Marco Vincenzo
    Rugge, Massimo
    Lahner, Edith
    Miceli, Emanuela
    Toh, Ban-Hock
    Genta, Robert M.
    De Block, Christophe
    Hershko, Chaim
    Di Sabatin, Antonio
    [J]. NATURE REVIEWS DISEASE PRIMERS, 2020, 6 (01)
  • [5] The changing face of chronic autoimmune atrophic gastritis: an updated comprehensive perspective
    Massironi, Sara
    Zilli, Alessandra
    Elvevi, Alessandra
    Invernizzi, Pietro
    [J]. AUTOIMMUNITY REVIEWS, 2019, 18 (03) : 215 - 222
  • [6] A Case of Pernicious Anemia Presenting With Severe Hemolysis
    Romero, Kaitlyn N.
    Patel, Falguni
    Rai, Oshin
    Quan, Austin
    Reddy, Pramod
    [J]. CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (12)
  • [7] Autoimmune gastritis, with or without pernicious anemia: epidemiology, risk factors, and clinical management
    Rustgi, Sheila D.
    Bijlani, Priyesha
    Shah, Shailja C.
    [J]. THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 2021, 14
  • [8] Severe megaloblastic anemia: Vitamin deficiency and other causes
    Socha, Daniel S.
    DeSouza, Sherwin, I
    Flagg, Aron
    Sekeres, Mikkael
    Rogers, Heesun J.
    [J]. CLEVELAND CLINIC JOURNAL OF MEDICINE, 2020, 87 (03) : 153 - 164
  • [9] Wang HY, 2018, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD004655.pub3, 10.1002/14651858.C.0004655.pub3]
  • [10] A Case of Pseudothrombotic Microangiopathy Associated with Pernicious Anemia
    Wathieu, Henri
    Bateman, Kristin M.
    [J]. JOURNAL OF GENERAL INTERNAL MEDICINE, 2021, 36 (06) : 1775 - 1777