Incongruence of Hemolysis, Elevated Liver Enzyme, Low-Platelet Count Syndrome (HELLP) and Preeclampsia Criteria in Pregnancy: Implications for Medical Education and Obstetrics Training

被引:0
|
作者
Jenkins, Jacob [1 ]
Ferozuddin, Aleena A. [1 ]
Mourad, Jad [1 ]
Abdulla, Zayna Z. [1 ]
Oviedo, Angelica [2 ]
机构
[1] Burrell Coll Osteopath Med, Physiol & Pathol, Las Cruces, NM USA
[2] Burrell Coll Osteopath Med, Pathol & Lab Med, Melbourne, FL 32901 USA
关键词
constructivism; diagnostic criteria; medical training; obstetrics education; pregnancy-related complications; preeclampsia; hellp syndrome;
D O I
10.7759/cureus.67211
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
There is conflicting information in the medical literature regarding hemolysis, elevated liver enzymes, low platelet count syndrome (HELLP) and preeclampsia and whether they are subsets of a single disease or distinct complications of pregnancy. In numerous places, HELLP is described as a severe form or later stage of preeclampsia. However, a detailed medical literature search utilizing NCBI, PubMed, and Elicit: The AI Research Assistant clearly demonstrates that HELLP and preeclampsia are distinct diseases. While they share similarities, each one has unique diagnostic criteria, pathophysiology, and treatment. We believe that these entities should be taught as separate entities to medical students and residents because this will result in better patient care. Medical educational theories, including constructivism, demonstrate that initial learning experiences heavily influence future learning. The joining of HELLP and preeclampsia in medical school teaching materials is detrimental to students' and trainees' long-term understanding of these two serious complications of pregnancy.
引用
收藏
页数:4
相关论文
共 50 条
  • [31] Clinical utility of strict diagnostic criteria for the HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome
    Audibert, F
    Friedman, SA
    Frangieh, AY
    Sibai, BM
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1996, 175 (02) : 460 - 464
  • [32] Maternal benefit of corticosteroid therapy in patients with HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome: Impact on the rate of regional anesthesia
    O'Brien, JM
    Shumate, SA
    Satchwell, SL
    Milligan, DA
    Barton, JR
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2002, 186 (03) : 475 - 479
  • [33] Spontaneous hepatic rupture caused by hemolysis, elevated liver enzymes, and low platelet count syndrome
    You, Je Sung
    Chung, Yong Eun
    Chung, Hyun Soo
    Joo, Youngseon
    Chung, Sung Phil
    Lee, Hahn Shick
    AMERICAN JOURNAL OF EMERGENCY MEDICINE, 2014, 32 (06) : 686.e3 - 686.e4
  • [34] Differentiation of acute fatty liver of pregnancy from syndrome of hemolysis, elevated liver enzymes and low platelet counts
    Minakami, Hisanori
    Morikawa, Mamoru
    Yamada, Takahiro
    Yamada, Takashi
    Akaishi, Rina
    Nishida, Ryutaro
    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 2014, 40 (03) : 641 - 649
  • [35] Hypertension in Hemolysis, Elevated Liver Enzyme, Low Platelet Syndrome is Associated with Increased Endothelin-1
    Wallace, Kedra
    Morris, Rachael
    Chatman, Krystal
    Moseley, Janae
    LaMarca, B. Babbette
    HYPERTENSION, 2013, 62 (03)
  • [36] Liver rupture in a 28-year-old primigravida with superimposed pre-eclampsia and hemolysis, elevated liver enzyme levels, and low platelet count syndrome
    Kaltofen, Till
    Grabmeier, Johanna
    Weissenbacher, Tobias
    Hallfeldt, Klaus
    Mahner, Sven
    Hutter, Stefan
    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 2019, 45 (05) : 1066 - 1070
  • [37] Immunohistological study in cases of HELLP syndrome (hemolysis, elevated liver enzymes and low platelets) and acute fatty liver of pregnancy
    Halim, A
    Kanayama, N
    ElMaradny, E
    Maehara, K
    Takahashi, A
    Nosaka, K
    Fukuo, S
    Amamiya, A
    Kobayashi, T
    Terao, T
    GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 1996, 41 (02) : 106 - 112
  • [38] Hypertension, Anxiety, and Blood-Brain Barrier Permeability Are Increased in Postpartum Severe Preeclampsia/Hemolysis, Elevated Liver Enzymes, and Low Platelet Count Syndrome Rats
    Wallace, Kedra
    Bean, Cynthia
    Bowles, Teylor
    Spencer, Shauna-Kay
    Randle, Wisdom
    Kyle, Patrick B.
    Shaffery, James
    HYPERTENSION, 2018, 72 (04) : 946 - 954
  • [39] Combined Immature Platelet Fraction and Schistocyte Count to Differentiate Pregnancy-Associated Thrombotic Thrombocytopenic Purpura from Severe Preeclampsia/Haemolysis, Elevated Liver Enzymes, and Low Platelet Syndrome (SPE/HELLP)
    El-Gamal, Rasha A.
    Mekawy, Mohamed A.
    Abd Elkader, Ayman M.
    Abdelbary, Haitham M.
    Fayek, Mary Z.
    INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION, 2020, 36 (02) : 316 - 323
  • [40] Different pathogenic mechanisms of early-onset preeclampsia, late-onset preeclampsia, and hemolysis, elevated liver enzymes, low platelet syndrome
    Sisti, Giovanni
    TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2020, 17 (01) : 77 - 78