Exercise and nutrition benefit skeletal muscle: From influence factor and intervention strategy to molecular mechanism

被引:9
作者
Feng, Lili [1 ]
Li, Bowen [1 ]
Yong, Su Sean [1 ]
Wu, Xiaonan [2 ]
Tian, Zhenjun [3 ]
机构
[1] Zhejiang Univ, Coll Educ, Phys Educ Dept, Hangzhou 310058, Peoples R China
[2] Natl Univ Def Technol, Informat & Commun Coll, Xian 710106, Peoples R China
[3] Shaanxi Normal Univ, Inst Sports Biol, Coll Phys Educ, Xian 710119, Peoples R China
基金
中国国家自然科学基金;
关键词
Skeletal muscle; Sarcopenia; Exercise; Diet; Exerkines; Signaling pathway; Satellite cells; WHOLE-BODY VIBRATION; SATELLITE CELLS; RESISTANCE EXERCISE; AEROBIC EXERCISE; OLDER WOMEN; MICE; SARCOPENIA; MASS; DYSFUNCTION; ACTIVATION;
D O I
10.1016/j.smhs.2024.02.004
中图分类号
G8 [体育];
学科分类号
04 ; 0403 ;
摘要
Sarcopenia is a progressive systemic skeletal muscle disease induced by various physiological and pathological factors, including aging, malnutrition, denervation, and cardiovascular diseases, manifesting as the decline of skeletal muscle mass and function. Both exercise and nutrition produce beneficial effects on skeletal muscle growth and are viewed as feasible strategies to prevent sarcopenia. Mechanisms involve regulating blood flow, oxidative stress, inflammation, apoptosis, protein synthesis and degradation, and satellite cell activation through exerkines and gut microbiomes. In this review, we summarized and discussed the latest progress and future development of the above mechanisms for providing a theoretical basis and ideas for the prevention and treatment of sarcopenia.
引用
收藏
页码:302 / 314
页数:13
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