Hematoporphyrin photodynamic therapy for treatment of pathological scar with ulceration: A case report

被引：0

作者：

Xia, Lianheng ^{[1
]}

Lv, Hang ^{[2
]}

Yu, Shaolei ^{[2
]}

Xiang, Xiaoqing ^{[3
]}

Li, Yanliang ^{[3
]}

Wang, Jiaxin ^{[1
]}

Ma, Guozhang ^{[4
]}

Gao, Jie ^{[1
]}

机构：

[1] Heilongjiang Univ Chinese Med, Affiliated Hosp 1, Dept Peripheral Vasc Dis, Harbin City, Heilongjiang Pr, Peoples R China

[2] Heilongjiang Univ Chinese Med, Affiliated Hosp 2, Harbin City, Heilongjiang Pr, Peoples R China

[3] Heilongjiang Univ Chinese Med, Harbin City, Heilongjiang Pr, Peoples R China

[4] Heilongjiang Prov Hosp, Dermatol Dept, Harbin City, Heilongjiang Pr, Peoples R China

来源：

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY | 2024年 / 49卷

基金：

中国国家自然科学基金;

关键词：

Cicatricial ulcer; Hematoporphyrine injection; Photodynamic therapy;

D O I：

10.1016/j.pdpdt.2024.104315

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Pathological scars result from abnormal wound healing and represent a fibrotic process in the repair of skin injuries. Post-burn scars are prone to malignant transformation, especially when ulceration occurs, raising concerns for precancerous lesions. We report a case of a 56-year-old female with a 50-year history of a large burn scar on her left forearm. The scar developed non-healing ulceration with local pain and itching over the past three years. Treatment with hematoporphyrin photodynamic therapy (HpD-PDT) led to resolution of the ulceration, thinning of the scar tissue, and significant alleviation of pain and itching. After a five-year follow-up, there has been no recurrence of ulceration, suggesting that photodynamic therapy effectively promotes wound healing in scarred tissue with ulcerations.

引用

页数：3

共 10 条

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