CYCLICAL PRIMING AS A NOVEL APPROACH TO INCREASE MESENCHYMAL STROMAL CELL EXTRACELLULAR VESICLE MANUFACTURING YIELD AND REPRODUCIBILITY

被引:0
|
作者
Larey, A. M. [1 ,2 ]
Adedipe, T. [3 ]
Marklein, R. [1 ,2 ]
机构
[1] Univ Georgia, Sch Chem Mat & Biomed Engn, Athens, GA USA
[2] Univ Georgia, Regenerat Biosci Ctr, Athens, GA USA
[3] Georgia Inst Technol, Coulter Dept Biomed Engn, Coll Engn, Atlanta, GA USA
关键词
mesenchymal stromal cell; priming; manufacturing;
D O I
暂无
中图分类号
Q813 [细胞工程];
学科分类号
摘要
350
引用
收藏
页码:E13 / E14
页数:2
相关论文
共 13 条
  • [1] Mesenchymal stromal cell derived extracellular vesicles as a therapeutic tool: immune regulation, MSC priming, and applications to SLE
    Wong, Christophe
    Stoilova, Ivana
    Gazeau, Florence
    Herbeuval, Jean-Philippe
    Fourniols, Thibaut
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [2] Mesenchymal stem cell extracellular vesicle vascularization bioactivity and production yield are responsive to cell culture substrate stiffness
    Powsner, Emily H.
    Kronstadt, Stephanie M.
    Nikolov, Kristin
    Aranda, Amaya
    Jay, Steven M.
    BIOENGINEERING & TRANSLATIONAL MEDICINE, 2025,
  • [3] Pooled Analysis of Mesenchymal Stromal Cell-Derived Extracellular Vesicle Therapy for Liver Disease in Preclinical Models
    Fang, Xinru
    Gao, Feiqiong
    Yao, Qigu
    Xu, Haoying
    Yu, Jiong
    Cao, Hongcui
    Li, Shibo
    JOURNAL OF PERSONALIZED MEDICINE, 2023, 13 (03):
  • [4] Mesenchymal stromal cell derived extracellular vesicles as a therapeutic tool: immune regulation, MSC priming, and applications to SLE ( vol 15 , 135545 , 2024)
    Wong, Christophe
    Stoilova, Ivana
    Gazeau, Florence
    Herbeuval, Jean-Philippe
    Fourniols, Thibaut
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [5] TOWARDS IMPROVED LARGE-SCALE MANUFACTURING PROCESSES OF MESENCHYMAL STROMAL CELL-DERIVED EXTRACELLULAR VESICLES
    Cunha, R.
    Calado, C.
    Cabral, J. M.
    da Silva, C. L.
    Fernandes-Platzgummer, A.
    CYTOTHERAPY, 2021, 23 (05) : S116 - S116
  • [6] Recent Advances in Extracellular Vesicle-Based Therapies Using Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells
    Bertolino, Giuliana Minani
    Maumus, Marie
    Jorgensen, Christian
    Noel, Daniele
    BIOMEDICINES, 2022, 10 (09)
  • [7] HIGH THROUGHPUT SCREENING OF MESENCHYMAL STROMAL CELL MORPHOLOGICAL RESPONSE TO INFLAMMATORY SIGNALS FOR BIOREACTOR-BASED MANUFACTURING OF IMMUNOMODULATORY EXTRACELLULAR VESICLES
    Larey, A. M.
    Daga, K. R.
    Campagna, C. E.
    Maughon, T. S.
    Spoerer, T.
    Chen, K.
    Marklein, R.
    CYTOTHERAPY, 2022, 24 (05) : S56 - S57
  • [8] High throughput screening of mesenchymal stromal cell morphological response to inflammatory signals for bioreactor-based manufacturing of extracellular vesicles that modulate microglia
    Larey, Andrew M.
    Spoerer, Thomas M.
    Daga, Kanupriya R.
    Morfin, Maria G.
    Hynds, Hannah M.
    Carpenter, Jana
    Hines, Kelly M.
    Marklein, Ross A.
    BIOACTIVE MATERIALS, 2024, 37 : 153 - 171
  • [9] Harmonised culture procedures minimise but do not eliminate mesenchymal stromal cell donor and tissue variability in a decentralised multicentre manufacturing approach
    Calcat-i-Cervera, Sandra
    Rendra, Erika
    Scaccia, Eleonora
    Amadeo, Francesco
    Hanson, Vivien
    Wilm, Bettina
    Murray, Patricia
    O'Brien, Timothy
    Taylor, Arthur
    Bieback, Karen
    STEM CELL RESEARCH & THERAPY, 2023, 14 (01)
  • [10] Harmonised culture procedures minimise but do not eliminate mesenchymal stromal cell donor and tissue variability in a decentralised multicentre manufacturing approach
    Sandra Calcat-i-Cervera
    Erika Rendra
    Eleonora Scaccia
    Francesco Amadeo
    Vivien Hanson
    Bettina Wilm
    Patricia Murray
    Timothy O’Brien
    Arthur Taylor
    Karen Bieback
    Stem Cell Research & Therapy, 14