Synthesis of triazole-fused tetracyclic spirooxindole derivatives via metal-free Huisgen cycloaddition

被引：1

作者：

Maiti, Sandip ^{[1
]}

Parui, Nabin ^{[1
]}

Halder, Joydev ^{[1
]}

Dash, Jyotirmayee ^{[1
]}

机构：

[1] Indian Assoc Cultivat Sci Jadavpur, Sch Chem Sci, Kolkata 7000032, India

来源：

CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 73期

基金：

英国惠康基金;

关键词：

STEREOSELECTIVE-SYNTHESIS; ISATINS; ALKYLATION; INHIBITOR; DESIGN;

D O I：

10.1039/d4cc02534b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report an efficient, metal free method for synthesizing tetracyclic spirooxindole derivatives from N-protected isatins and propargyl bromide via Huisgen cycloaddition. This simple and practicle method provides access to spirooxindoles containing five-, six-, or seven-membered rings fused to a triazole ring.

引用

页码：10009 / 10012

页数：4

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