Cyanidin-3-o-glucoside liposome: Preparation via a green method and antioxidant activity in GES-1 cells

被引：26
作者：
Liang, Tisong [1 ]
Guan, Rongfa [1 ]
Quan, Zhao [1 ]
Tao, Qingfeng [1 ]
Liu, Zhenfeng [2 ]
Hu, Qiang [3 ]
机构：
[1] China Jiliang Univ, Zhejiang Prov Key Lab Biometrol & Inspect & Quara, Hangzhou 310018, Zhejiang, Peoples R China
[2] Chiatai Qing Chun Bao Pharmaceut Co LTD, 551 Xixi Rd, Hangzhou 310023, Zhejiang, Peoples R China
[3] Hangzhou Zhiweiguan Food Co LTD, Fengdu Ind Pk, Hangzhou 311115, Zhejiang, Peoples R China
来源：
FOOD RESEARCH INTERNATIONAL | 2019年 / 125卷
基金：
中国国家自然科学基金; 国家重点研发计划;
关键词：
C3G; C3G liposomes; GES-1cells; Antioxidant activity; Color stability; Mitochondria structure; LOADED LIPOSOMES; STABILITY; ANTHOCYANINS; COLOR; RICH;
D O I：
10.1016/j.foodres.2019.108648
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Cyanidin-3-O-glucoside (C3G) liposomes was used to improve the stability and antioxidant activity of C3G through a green thin-film dispersion method. The characteristics, stability and the effect of C3G liposomes on GES-1 cells were explored. Results showed that the particle size and encapsulation efficiency (EE%) of C3G liposomes were 258.9 +/- 5.06 nM and 77.5%, respectively. DPPH assay showed that liposomes encapsulation can improve the antioxidant of C3G, while the ABTS assay was opposite. Stability study showed the C3G liposome were unstable under extended storage time. The effects of C3G liposomes on GES-1 cells showed that C3G liposomes can decrease the ROS levels of GES-1 and had negligible effects on cell viability and mitochondria) structure. These findings suggested that liposomes could be used as a carrier system to improve the stability of C3G.
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页数：9
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