Quality of life is an independent predictor of mortality in patients with heart failure: a prospective cohort study from the Colombian heart failure registry (RECOLFACA)

被引:1
作者
Gomez-Mesa, Juan Esteban [1 ,2 ]
Luna-Bonilla, Paula [3 ]
Echeverria, Luis Eduardo [4 ]
Rivera-Toquica, Alex [5 ,6 ,7 ]
Jurado-Arenales, Adriana Milena [8 ]
Orozco, Maria Johanna [9 ]
Buitrago-Malaver, Lilia Andrea [10 ]
Rivera, Edilma L. [11 ]
Gonzalez, Diana Veronica [12 ]
Coronado-Villa, Estefanny [13 ]
Toro-Cardona, Olga Cristina [14 ]
Lopez-Montes, Cristian Alexander [15 ]
Vargas-Marquez, Ludy Yanet [16 ]
Martinez-Camargo, Silvia [17 ]
Agudelo-Perez, Adriana [18 ]
Vivas-Mayor, Marcela [19 ]
Nino, Lina Maria [20 ]
Mejia-Cadavid, Luz Aida [21 ]
Aponte-Romero, Luisa Fernanda [22 ]
Erazo, Maria Jose [23 ]
Garcia-Barrera, Maria [24 ]
Meza-Roque, Julio Armando [25 ]
Rios-Sanchez, Viviana [26 ]
Torres-Moreno, Fabian [27 ]
Castaneda-M, Jenny [28 ]
Gallego, Cesar A. [29 ]
Martinez, Fanny Esther [30 ]
Blandon-Cordoba, Carmen Jineth [31 ]
Silva-Carmona, Monica [32 ]
Saldarriaga, Clara [33 ]
机构
[1] Fdn Valle del Lili, Dept Cardiol, Cra 98 18-49, Cali 760026, Colombia
[2] Univ Icesi, Dept Hlth Sci, Cali, Colombia
[3] Soc Colombiana Cardiol & Cirugia Cardiovasc, Dept Clin Records, Bogota, Colombia
[4] Fdn Cardiovasc Colombia FCV, Dept Cardiol, Floridablanca, Colombia
[5] Ctr Med Corazon, Dept Cardiol, Pereira, Colombia
[6] Clin Rosales, Dept Cardiol, Pereira, Colombia
[7] Univ Tecnol Pereira, Dept Cardiol, Pereira, Colombia
[8] Fdn Cardiovasc Colombia FCV, Dept Heart Failure, Bucaramanga, Colombia
[9] Gobernac Valle, Adm Dept Inst Dev, Cali, Colombia
[10] Univ Libre, Fac Hlth, Pereira, Colombia
[11] Hosp Univ Fdn Valle del Lili, Dept Cardiol, Cali, Colombia
[12] Fdn Santafe Bogota, Dept Cardiol, Bogota, Colombia
[13] Salud Social IPS, Dept Cardiol, Barranquilla, Colombia
[14] Cardiol Siglo XXI, Dept Cardiol, Ibague, Colombia
[15] AVIDANTI, Serv Hemodynam Electrophysiol, Manizales, Colombia
[16] Red Salud Integral IPS, Cardiol Unit, Norte De Santander, Colombia
[17] Fdn Clin Shaio, Dept Cardiol, Bogota, Colombia
[18] External Consulting, Clin Cardio VID, Medellin, Colombia
[19] DIME Clin Neurocardiovasc, Heart Failure & Transplant Unit, Cali, Colombia
[20] Inst Corazon Bucaramanga, Dept Cardiol, Bucaramanga, Colombia
[21] Clin Rosario, Res Dept, Medellin, Colombia
[22] Hosp Univ San Ignacio, Heart Failure Clin & Heart Transplant, Bogota, Colombia
[23] Hosp Univ Sincelejo, Dept Nursing, Sincelejo, Colombia
[24] Clin Iberoamer, Heart Failure Dept, Barranquilla, Colombia
[25] Unimed, Dept Nursing, Pasto, Colombia
[26] Ctr Cardiovasc Somer Incare, Noninvas Diagnost Aids Unit, Rionegro, Colombia
[27] IQVIA RDS Colombia, Country Site Activat, Bogota, DC, Colombia
[28] Hosp Cardiovasc Cundinamarca, Heart Failure Dept, Cundinamarca, Colombia
[29] Adult Intens Care Unit, Clin Occidente, Cali, Colombia
[30] Alcaldia Municipal Arboletes, Dept Publ Hlth, Arboletes, Colombia
[31] Cardiodiagnost Choco, Dept Cardiol, Quibdo, Colombia
[32] Clin Oncol Aurora, Nursing Dept, Pasto, Colombia
[33] Clin Cardio VID, Dept Cardiol, Medellin, Colombia
关键词
Colombia; Heart Failure; Mortality; Quality of life; CITY CARDIOMYOPATHY QUESTIONNAIRE; HEALTH-STATUS; EJECTION FRACTION; DEPRESSION; RISK; HOSPITALIZATION; ASSOCIATION; INSIGHTS; ANXIETY; DISEASE;
D O I
10.1093/eurjcn/zvae117
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aim: Patients with Heart Failure (HF) commonly have poor quality of life (QoL), secondary to the persistence and severity of HF symptoms. We aimed to evaluate the prognostic value of QoL measures on all-cause mortality in patients with HF from the Colombian registry of heart failure (RECOLFACA). Methods and results: We analyzed data from patients registered in RECOLFACA during 2017-2019. QoL was measured using the EuroQol-5D questionnaire (EQ-5D). From the questionnaire, two independent predictors of mortality were obtained, the visual analogue scale (VAS) and the utility score (US). Primary outcome was all-cause mortality, and secondary variables evaluated were demographic factors, comorbidities, NYHA classification, medications used and laboratory test results. To analyze survival among patients, the Kaplan-Meier method and the hierarchical Cox proportional-hazards regression model were used. This study included 2514 patients from RECOLFACA. Most patients were male (57.6%), and mean age was 67.8 years. Mean value and standard deviation (SD) of the VAS score was 78.8 +/- 20.1 points, while the mean and SD of the US score was 0.81 +/- 0.20. As the Kaplan-Meier curve illustrated, patients in the lower quartiles of both VAS and US scores had a significantly higher probability of mortality (log-rank test: p<0.001 for both scores). Conclusion: QoL, as calculated by the EQ-5D questionnaire, served as an independent predictor of mortality in patients from RECOLFACA. Further studies may be needed to evaluate whether provision of optimizing therapies and follow-up care based on patients' perceived QoL reduces short- and long-term mortality rates in this population.
引用
收藏
页码:71 / 80
页数:10
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