Post-Traumatic Stress Disorder and Risk of Parkinson's Disease in a Veteran Cohort

被引:0
作者
Weaver, Frances M. [1 ,2 ]
Cao, Lishan [1 ]
Stroupe, Kevin T. [1 ,2 ]
Gonzalez, Beverly [3 ]
Brown, Ethan [4 ]
Colletta, Kalea [5 ]
Tanner, Caroline M. [4 ,7 ]
Goldman, Samuel M. [6 ,7 ]
机构
[1] Edward Hines Jr VA Hosp, Ctr Innovat Complex Chron Healthcare CINCCH, Hines, IL 60141 USA
[2] Loyola Univ, Parkinson Sch Hlth Sci & Publ Hlth, Maywood, IL USA
[3] Edward Hines Jr VA Hosp, Cooperat Studies Coordinating Ctr, Hines, IL USA
[4] Univ Calif San Francisco, Weill Inst Neurosci, Dept Neurol, San Francisco, CA USA
[5] Edward Hines Jr VA Hosp, Neurol Serv, Hines, IL USA
[6] Univ Calif San Francisco, Div Occupat Environm & Climate Med, San Francisco, CA USA
[7] San Francisco VA Hlth Care Syst, Res Serv, San Francisco, CA USA
关键词
PTSD; Parkinson's disease; Veterans; epidemiology; stress; PREVALENCE;
D O I
10.3233/JPD-240098
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
. Post-traumatic stress disorder (PTSD) may be a risk factor for Parkinson's disease (PD). We examined the relation between PTSD and PD in a cohort of 158,122 Veterans who had any Veterans Health Administration (VHA) or Medicare health care utilization between 10/1/1999-2/17/2021. Using a nested case-control design we matched 10 controls to each Veteran with PD by sex, race, and rank. In conditional logistic regression models adjusted for camp and smoking, a PTSD diagnosis was significantly associated with PD (OR = 1.35; p = 0.0002); odds were higher if PTSD was coded before PD (OR =1.53, p < 0.0001). PTSD may be a risk factor for PD.
引用
收藏
页码:1265 / 1269
页数:5
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