Consequences of Maternal Vitamin D Deficiency on Newborn Health

被引:7
作者
Dragomir, Ramona Elena [1 ]
Toader, Daniela Oana [2 ]
Mutu, Daniela Elena Gheoca [3 ]
Dogaru, Iulian Alexandru [1 ,3 ]
Raducu, Laura [4 ]
Tomescu, Laurentiu Cezar [5 ]
Moleriu, Lavinia Cristina [6 ]
Bordianu, Anca [4 ]
Petre, Ion [6 ]
Stanculescu, Ruxandra [1 ]
机构
[1] Carol Davila Univ Med & Pharm, Doctoral Sch, Bucharest 020021, Romania
[2] Carol Davila Univ Med & Pharm, Dept Obstet & Gynecol, Bucharest 020021, Romania
[3] Carol Davila Univ Med & Pharm, Dept Morphol Sci, Discipline Anat, Bucharest 020021, Romania
[4] Carol Davila Univ Med & Pharm, Discipline Plast Surg, Bucharest 020021, Romania
[5] Ovidius Univ, Dept Phys, Constanta 900527, Romania
[6] Victor Babes Univ Med & Pharm, Dept Funct Sci, Discipline Informat & Med Biostat, Timisoara 300041, Romania
来源
LIFE-BASEL | 2024年 / 14卷 / 06期
关键词
vitamin D in pregnancy; vitamin D deficiency; newborn outcome; PREGNANT-WOMEN; D SUPPLEMENTATION; D INSUFFICIENCY; UNITED-STATES; BODY-MASS; OBESITY; ASSOCIATION; PREVALENCE; FAT; RISK;
D O I
10.3390/life14060714
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background and Objectives: Maternal-fetal gestational pathology is one of the biggest challenges in the field of health at this moment. The current study is designed to determine the effects of vitamin D on pregnancy, starting with the idea that impairment of vitamin D status is thought to be correlated with impairment of the newborn's health. Materials and Methods: In this retrospective study, we tried to establish the link between vitamin D deficiency and maternal characteristics and also how it impacted the clinical status of the newborn. We analyzed a group of 260 patients: 130 pregnant women and 130 newborns, in whom vitamin D status was detected using the serum levels of 25-hydroxyvitamin D (25-(OH)D). Results: The results showed that vitamin D deficiency has a high incidence among pregnant women, as was presented in many important international studies. Our study also showed a positive, direct correlation between the mother's and newborn's vitamin D status. Conclusions: Taking into consideration that vitamin D deficiency has been correlated with many complications, both in maternal and newborn health, a serum level determination of 25-(OH)D is necessary in the first trimester of pregnancy, and after that, adequate supplementation is necessary in order to prevent any negative effects.
引用
收藏
页数:15
相关论文
共 58 条
[1]   Vitamin D status in early pregnancy and risk of preeclampsia [J].
Achkar, Madonna ;
Dodds, Linda ;
Giguere, Yves ;
Forest, Jean-Claude ;
Armson, B. Anthony ;
Woolcott, Christy ;
Agellon, Sherry ;
Spencer, Anne ;
Weiler, Hope A. .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2015, 212 (04) :511.e1-511.e7
[2]   Association between maternal serum 25-hydroxyvitamin D level and pregnancy and neonatal outcomes: systematic review and meta-analysis of observational studies [J].
Aghajafari, Fariba ;
Nagulesapillai, Tharsiya ;
Ronksley, Paul E. ;
Tough, Suzanne C. ;
O'Beirne, Maeve ;
Rabi, Doreen M. .
BMJ-BRITISH MEDICAL JOURNAL, 2013, 346
[3]   Mode of delivery and maternal vitamin D deficiency: an optimized intelligent Bayesian network algorithm analysis of a stratified randomized controlled field trial [J].
Amiri, Mina ;
Rostami, Maryam ;
Sheidaei, Ali ;
Fallahzadeh, Aida ;
Ramezani Tehrani, Fahimeh .
SCIENTIFIC REPORTS, 2023, 13 (01)
[4]   Vitamin D deficiency 2.0: an update on the current status worldwide [J].
Amrein, Karin ;
Scherkl, Mario ;
Hoffmann, Magdalena ;
Neuwersch-Sommeregger, Stefan ;
Koestenberger, Markus ;
Berisha, Adelina Tmava ;
Martucci, Gennaro ;
Pilz, Stefan ;
Malle, Oliver .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2020, 74 (11) :1498-1513
[5]  
[Anonymous], About us
[6]  
Ashley B, 2022, ELIFE, V11, DOI [10.7554/eLife.71094, 10.7554/eLife.71094.sa0, 10.7554/eLife.71094.sa1, 10.7554/eLife.71094.sa2]
[7]  
Baydaa Y.I., 2023, J. Popul. Ther. Clin. Pharmacol, V30, P35
[8]   Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes [J].
Bischoff-Ferrari, Heike A. ;
Giovannucci, Edward ;
Willett, Walter C. ;
Dietrich, Thomas ;
Dawson-Hughes, Bess .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2006, 84 (01) :18-28
[9]   High prevalence of vitamin D insufficiency in black and white pregnant women residing in the northern United States and their neonates [J].
Bodnar, Lisa M. ;
Simhan, Hyagriv N. ;
Powers, Robert W. ;
Frank, Michael P. ;
Cooperstein, Emily ;
Roberts, James M. .
JOURNAL OF NUTRITION, 2007, 137 (02) :447-452
[10]  
Bonte DC, 2017, MATER PLAST, V54, P678