Indocyanine green lymphography in the congenital chylothorax and chylous ascites

被引:1
作者
Lin, T. [1 ]
Shibasaki, J. [1 ]
Yamamoto, K. [2 ]
Shimokaze, T. [1 ]
Toyoshima, K. [1 ]
机构
[1] Kanagawa Childrens Med Ctr, Dept Neonatol, 2-138-4 Mutsukawa,Minami Ku, Yokohama 2328555, Japan
[2] Yokohama City Univ, Sch Med, Dept Biostat, Yokohama, Japan
关键词
Ascites; down syndrome; neonate; noonan syndrome; pleural effusion; LYMPHATIC DYSPLASIA; PLEURAL EFFUSION; CHILDREN;
D O I
10.3233/NPM-230171
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
BACKGROUND: The prognosis of congenital chylothorax and ascites ranges from spontaneous resolution to death, but no established examination exists to predict the prognosis. We aimed to develop a clinically useful method to evaluate lymphatic abnormalities using indocyanine green (ICG) lymphography in infants with congenital chylothorax and ascites. METHODS: We retrospectively evaluated infants with congenital chylothorax and chylous ascites who underwent ICG lymphography in our hospital between 2012 and 2022. The ICG lymphography findings was evaluated. We defined the dermal backflow in the trunk as the lymphatic flow from the end of the limb back through the lymphatic vessels on the surface of the trunk. The association between the dermal backflow in the trunk and clinical outcomes, as follows, are investigated: the duration of the drainage period, the duration of endotracheal intubation, and the length of hospital stay. RESULTS: Twenty infants had a dermal backflow in the trunk, and ten did not. Clinical outcomes in infants with and without dermal backflow in the trunk were as follows (median): the duration of the drainage period (20 vs. 0 days, p = 0.001), the duration of endotracheal intubation (12 vs. 2 days, p = 0.04), and the length of hospital stay (62 vs. 41 days, p = 0.04), respectively. In multivariate linear regression analysis adjusted for gestational age, the duration of the drainage period was correlated with the dermal backflow in the trunk [exp(B) = 2.62; p = 0.003]. CONCLUSIONS: The dermal backflow in the trunk in ICG lymphography was useful in predicting the clinical course of congenital chylothorax and ascites.
引用
收藏
页码:247 / 254
页数:8
相关论文
共 17 条
[1]   Congenital chylothorax [J].
Attar, Mohammad A. ;
Donn, Steven M. .
SEMINARS IN FETAL & NEONATAL MEDICINE, 2017, 22 (04) :234-239
[2]   Lymphatic dysplasias in newborns and children: The role of lymphoscintigraphy [J].
Bellini, Carlo ;
Boccardo, Francesco ;
Campisi, Corradino ;
Villa, Giuseppe ;
Taddei, Gioconda ;
Traggiai, Cristina ;
Boniou, Eugenio .
JOURNAL OF PEDIATRICS, 2008, 152 (04) :587-589
[3]  
Bengtsson B-OS, 2013, NEOREVIEWS, V14, P600
[4]   Congenital chylothorax: a prospective nationwide epidemiological study in Germany [J].
Bialkowski, Anja ;
Poets, Christian F. ;
Franz, Axel R. .
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 2015, 100 (02) :F169-F172
[5]   Chylothorax in children -: Guidelines for diagnosis and management [J].
Büttiker, V ;
Fanconi, S ;
Burger, R .
CHEST, 1999, 116 (03) :682-687
[6]   Congenital chylothorax: from foetal life to adolescence [J].
Caserio, S. ;
Gallego, C. ;
Martin, P. ;
Moral, M. T. ;
Pallas, C. R. ;
Galindo, A. .
ACTA PAEDIATRICA, 2010, 99 (10) :1571-1577
[7]  
Chen Eric, 2011, Semin Intervent Radiol, V28, P63, DOI 10.1055/s-0031-1273941
[8]   Thoracic lymphangiomas, lymphangiectasis, lymphangiomatosis, and lymphatic dysplasia syndrome [J].
Faul, JL ;
Berry, GJ ;
Colby, TV ;
Ruoss, SJ ;
Walter, MB ;
Rosen, GD ;
Raffin, TA .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2000, 161 (03) :1037-1046
[9]   Near-Infrared Fluorescence Lymphatic Imaging of a Toddler With Congenital Lymphedema [J].
Greives, Matthew R. ;
Aldrich, Melissa B. ;
Sevick-Muraca, Eva M. ;
Rasmussen, John C. .
PEDIATRICS, 2017, 139 (04)
[10]   Flow Pattern Classification in Lymphatic Malformations by Indocyanine Green Lymphography [J].
Kato, Motoi ;
Watanabe, Shoji ;
Iida, Takuya ;
Watanabe, Azusa .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2019, 143 (03) :558E-564E