Kaposi Sarcoma in Two Lung Transplant Recipients: A Single-Center Experience

被引：0
作者：
Nathani, Avantika [1 ]
Lum, Jessica [1 ]
Gadre, Shruti [1 ]
Lane, Charles [1 ]
Akindipe, Olufemi [1 ]
Sethi, Sonali [1 ]
Mehta, Atul [1 ]
Turowski, Jason [1 ]
Tsuang, Wayne [1 ]
Arrossi, Andrea Valeria [2 ]
Budev, Marie [1 ]
机构：
[1] Cleveland Clin, Resp Inst, Cleveland, OH USA
[2] Cleveland Clin, Pathol & Lab Med, Cleveland, OH USA
来源：
TRANSPLANTATION PROCEEDINGS | 2024年 / 56卷 / 07期
关键词：
HUMAN-IMMUNODEFICIENCY-VIRUS; SOLID-ORGAN DONORS; HEPATITIS-B; SIROLIMUS; RISK; MULTICENTER; INFECTION; DIAGNOSIS;
D O I：
10.1016/j.transproceed.2024.07.004
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Kaposi's ' s Sarcoma (KS) is a malignant vascular tumor commonly seen in immunocompromised individuals, particularly patients with acquired immunodeficiency fi ciency syndrome. Lung transplant recipients are at high risk of developing KS due to a strong immunosuppressive regimen that can lead to donor-derived infection or reactivation of recipient human herpesvirus 8, the causative organism for KS. In this overview, we describe 2 lung transplant recipients who developed pulmonary KS with poor outcomes, reviewing the diagnosis, bronchoscopy fi ndings, and treatment and surveillance strategies for pulmonary KS.
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收藏
页码：1639 / 1645
页数：7
相关论文
共 38 条
[1]  
Abara WE, 2019, MMWR-MORBID MORTAL W, V68, P61, DOI 10.15585/mmwr.mm6803a2
[2]  
[Anonymous], 1872, Arch. Dermatol. Syph, V4, P265, DOI DOI 10.1007/BF01830024
[3]   Donor-derived human herpesvirus 8 infection with Kaposi sarcoma and Kaposi sarcoma inflammatory cytokine syndrome in a heart transplant recipient: A case report [J].
Antonio, Russo ;
Laura, Giovannini ;
Nicolina, Conti ;
Elena, Sabattini ;
Luca, Vizioli ;
Tiziana, Lazzarotto ;
Luciano, Potena ;
Davide, Pacini ;
Nazzareno, Galie' .
TRANSPLANT INFECTIOUS DISEASE, 2021,
[4]   Human Herpes Virus 8 in Solid Organ Transplantation [J].
Ariza-Heredia, Ella J. ;
Razonable, Raymund R. .
TRANSPLANTATION, 2011, 92 (08) :837-844
[5]   Human herpesvirus 8 DNA load in leukocytes of human immunodeficiency virus-infected subjects: Correlation with the presence of Kaposi's sarcoma and response to anticytomegalovirus therapy [J].
Boivin, G ;
Gaudreau, A ;
Toma, E ;
Lalonde, R ;
Routy, JP ;
Murray, G ;
Handfield, J ;
Bergeron, MG .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (02) :377-380
[6]   Risk of Kaposi sarcoma after solid organ transplantation in the United States [J].
Cahoon, Elizabeth K. ;
Linet, Martha S. ;
Clarke, Christina A. ;
Pawlish, Karen S. ;
Engels, Eric A. ;
Pfeiffer, Ruth M. .
INTERNATIONAL JOURNAL OF CANCER, 2018, 143 (11) :2741-2748
[7]   Multicenter Prospective Study for Laboratory Diagnosis of HHV8 Infection in Solid Organ Donors and Transplant Recipients and Evaluation of the Clinical Impact After Transplantation [J].
Chiereghin, Angela ;
Barozzi, Patrizia ;
Petrisli, Evangelia ;
Piccirilli, Giulia ;
Gabrielli, Liliana ;
Riva, Giovanni ;
Potenza, Leonardo ;
Cappelli, Gianni ;
De Ruvo, Nicola ;
Libri, Irene ;
Maggiore, Umberto ;
Morelli, Maria Cristina ;
Potena, Luciano ;
Todeschini, Paola ;
Gibertoni, Dino ;
Labanti, Manuel ;
Sangiorgi, Gabriela ;
La Manna, Gaetano ;
Pinna, Antonio Daniele ;
Luppi, Mario ;
Lazzarotto, Tiziana .
TRANSPLANTATION, 2017, 101 (08) :1935-1944
[8]   Fatal donor-derived Kaposi sarcoma following liver transplantation [J].
Copeland, Matthew Moore McCrea ;
Trainor, James ;
Cash, W. Johnny ;
Braniff, Conor .
BMJ CASE REPORTS, 2021, 14 (06)
[9]   Donor-derived human herpesvirus 8 and development of Kaposi sarcoma among 6 recipients of organs from donors with high-risk sexual and substance use behavior [J].
Dollard, Sheila C. ;
Annambhotla, Pallavi ;
Wong, Phili ;
Meneses, Katherine ;
Amin, Minal M. ;
La Hoz, Ricardo M. ;
Lease, Erika D. ;
Budev, Maria ;
Arrossi, Andrea Valeria ;
Basavaraju, Sridhar, V ;
Thomas, Christie P. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2021, 21 (02) :681-688
[10]   Donor-derived human herpes virus 8-related Kaposi's sarcoma in renal allograft ureter [J].
Dudderidge, T. J. ;
Khalifa, M. ;
Jeffery, R. ;
Amlot, P. ;
Al-Akraa, M. ;
Sweny, P. .
TRANSPLANT INFECTIOUS DISEASE, 2008, 10 (03) :221-226
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