Fatigue has been identified as a leading contributor to incidents and accidents within high-risk industries, in particular, the aviation sector. Traditional approaches used to mitigate fatigue, predominantly for air traffic controllers and flight crew, have largely focused on duty time limitations. FRMS is a data-driven means of continuously monitoring and managing fatigue-related safety risks, based on scientific principles and knowledge as well as operational experience, which aim to ensure relevant personnel are performing at adequate levels of alertness. It allows operators to adapt policies, procedures and practices to the specific conditions that create fatigue in a particular aviation setting. The ages of 36 participants in this study were from 23 years to 58 years old. The results demonstrated that ATCO's alertness indicate as functioning at a high level of alertness between 9 am and 5 pm during working hours. ATCOs' alertness levels deteriorated between working day-1 to day-5. Furthermore, there are significant differences over the 8 working hours per day among 5 working days. Particularly, the 6th, 7th and 8th working hours demonstrate much worsened alertness on day-4 and day-5. The pro-active approach of FRMS is to increase ATCOs fatigue resilience to cope with demanding situations while ATCOs are on position and while resting on breaks. FRMS is data driven, and data is collected from the operation, fatigue management decisions are made against this data, and the measurements that are required can be identified and implemented to improve the safety of operations.