Direct C-H Alkylation of Naphthoquinone with Acetone and 1,3-Dicarbonyl Compounds via Radical Cross Dehydrogenation Coupling

被引：0

作者：

Ou, Jiankang ^{[1
]}

Liu, Haoyu ^{[1
]}

Fang, Zeguo ^{[1
]}

Zhang, Qian ^{[1
]}

Li, Dong ^{[1
]}

机构：

[1] Hubei Univ Technol, Sch Mat & Chem Engn, New Mat & Green Mfg Talent Intro & Innovat Demonst, Wuhan 430068, Peoples R China

来源：

CHEMISTRYSELECT | 2024年 / 9卷 / 28期

关键词：

Alkylation; Naphthoquinone; Acetone; 1,3-Dicarbonyl compounds; Cross dehydrogenation coupling; METAL-FREE; QUINONES; FUNCTIONALIZATION; ARYLATION; DERIVATIVES; ROUTE;

D O I：

10.1002/slct.202402061

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A direct C-H alkylation of naphthoquinones with acetone and 1,3-dicarbonyl compounds was developed to construct C-C bonds of alkyl-substituted naphthoquinone derivatives. It proceeded through an oxidative radical cross dehydrogenation coupling process under simple and mild conditions. This method provides a facile and efficient route for synthesis of functionalized naphthoquinones from readily available feedstocks. Construction of C-C bonds of alkyl-substituted naphthoquinones through C-H/C-H cross dehydrogenation coupling of naphthoquinones with acetone and 1,3-dicarbonyl compounds was developed. image

引用

页数：4

共 42 条

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