Fibrolamellar Carcinoma: A Rare Liver Neoplasm

被引：0

作者：

Apumayta, Elily D. ^{[1
]}

Kahlam, Aaron ^{[2
]}

Ruiz, Eloy F. ^{[2
]}

机构：

[1] Inst Nacl Enfermedades Neoplas, Dept Abdominal Surg, Lima, Peru

[2] Rutgers New Jersey Med Sch, Dept Internal Med, Newark, NJ 07103 USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 04期

关键词：

hepatocellular; carcinoma; liver cancer; peru; fibrolamellar carcinoma; PROGNOSIS;

D O I：

10.7759/cureus.59006

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Fibrolamellar carcinoma is a rare liver tumor, with most cases arising in people younger than 40 years of age. We present a case series of five patients with histological confirmation of fibrolamellar carcinoma who had liver resection as the primary treatment. The median age of diagnosis was 24 years with nonspecific clinical manifestations in otherwise healthy patients. Alpha-fetoprotein levels were widely variable. Patients had classical imaging, macroscopic, and microscopic findings. Most of our patients underwent a hemihepatectomy and 60% recurred after the first year.

引用

页数：10

共 13 条

[1] Predictors of Outcome in Patients With Fibrolamellar Carcinoma: Analysis of the National Cancer Database [J].

Assi, Hussein A. ;

Mukherjee, Sarbajit ;

Machiorlatti, Michael ;

Vesely, Sara ;

Pareek, Vipul ;

Hatoum, Hassan .

ANTICANCER RESEARCH, 2020, 40 (02) :847-855

[2] Management of fibrolamellar hepatocellular carcinoma [J].

Chaudhari, Vikram A. ;

Khobragade, Krunal ;

Bhandare, Manish ;

Shrikhande, Shailesh V. .

CHINESE CLINICAL ONCOLOGY, 2018, 7 (05)

[3] FIBROLAMELLAR HEPATOCARCINOMA - CLINICAL, RADIOLOGIC, AND PATHOLOGICAL FEATURES [J].

FRANCIS, IR ;

AGHA, FP ;

THOMPSON, NW ;

KEREN, DF .

GASTROINTESTINAL RADIOLOGY, 1986, 11 (01) :67-72

[4] Imaging Features of Fibrolamellar Hepatocellular Carcinoma [J].

Ganeshan, Dhakshinamoorthy ;

Szklaruk, Janio ;

Kundra, Vikas ;

Kaseb, Ahmed ;

Rashid, Asif ;

Elsayes, Khaled .

AMERICAN JOURNAL OF ROENTGENOLOGY, 2014, 202 (03) :544-552

[5] Fibrolamellar carcinoma: Challenging the challenge [J].

Lamarca, Angela ;

Frizziero, Melissa ;

Fulton, Alexander ;

McNamara, Mairead G. ;

Filobbos, Rafik ;

Hubner, Richard A. ;

Wardell, Steve ;

Valle, Juan W. .

EUROPEAN JOURNAL OF CANCER, 2020, 137 :144-147

[6] A Systematic Review: Treatment and Prognosis of Patients with Fibrolamellar Hepatocellular Carcinoma [J].

Mavros, Michael N. ;

Mayo, Skye C. ;

Hyder, Omar ;

Pawlik, Timothy M. .

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2012, 215 (06) :820-830

[7] Elevated Serum α-Fetoprotein is Associated with Abbreviated Survival for Patients with Fibrolamellar Hepatocellular Carcinoma Who Undergo a Curative Resection [J].

McDonald, James D. ;

Gupta, Shreya ;

Shindorf, Mackenzie L. ;

Gamble, Lauren A. ;

Ruff, Samantha M. ;

Drake, Justin ;

Heller, Theo ;

Wan, Jim Y. ;

Dickson, Paxton, V ;

Glazer, Evan S. ;

Davis, Jeremy L. ;

Deneve, Jeremiah L. ;

Hernandez, Jonathan M. .

ANNALS OF SURGICAL ONCOLOGY, 2020, 27 (06) :1900-1905

[8] Fibrolamellar carcinoma: An entity all its own [J].

O'Neill, Allison F. ;

Church, Alanna J. ;

Perez-Atayde, Antonio R. ;

Shaikh, Raja ;

Marcus, Karen J. ;

Vakili, Khashayar .

CURRENT PROBLEMS IN CANCER, 2021, 45 (04)

[9] Fibrolamellar Hepatocellular Carcinoma: A Population-Based Observational Study [J].

Ramai, Daryl ;

Ofosu, Andrew ;

Lai, Jonathan K. ;

Gao, Zu-Hua ;

Adler, Douglas G. .

DIGESTIVE DISEASES AND SCIENCES, 2021, 66 (01) :308-314

[10] Hepatocellular carcinoma surgery outcomes in the developing world: A 20-year retrospective cohort study at the National Cancer Institute of Peru [J].

Ruiz, Eloy ;

Rojas, Teresa Rojas ;

Berrospi, Francisco ;

Chavez, Ivan ;

Luque, Carlos ;

Cano, Luis ;

Doimi, Franco ;

Pineau, Pascal ;

Deharo, Eric ;

Bertani, Stephane .

HELIYON, 2016, 2 (01)

← 1 2 →