Advancements in the Synthesis of Triazolopyrimidines

被引：1

作者：

Singh, Sushma ^{[1
]}

Lakhia, Raman ^{[2
]}

Yadav, Sidhant ^{[3
]}

Devi, Poonam ^{[2
]}

Yadav, Karmvati ^{[3
]}

Chaudhri, Vishwas ^{[4
]}

Pundeer, Rashmi ^{[3
]}

机构：

[1] Govt Coll, Dept Chem, Hisar 125001, Haryana, India

[2] Kurukshetra Univ, Dept Chem, Kurukshetra 136119, Haryana, India

[3] Indira Gandhi Univ, Dept Chem, Rewari, Haryana, India

[4] JC Bose Univ Sci & Technol YMCA Faridabad, Dept Chem, Faridabad, India

来源：

CURRENT ORGANIC CHEMISTRY | 2024年 / 28卷 / 20期

关键词：

Triazolopyrimidine; synthetic advancement; fused heterocycles; biological activity; therapeutic applications; ONE-POT; 1,3,2-BENZODIAZAPHOSPHORINAN-4-ONE STRUCTURE; MULTICOMPONENT SYNTHESIS; ANTITUMOR-ACTIVITY; DERIVATIVES; CHEMISTRY; DESIGN; COMPLEXES; PRODUCT; ANALOGS;

D O I：

10.2174/0113852728313437240607095009

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The triazolopyrimidine scaffold indeed holds a prominent place in medicinal chemistry due to its versatile pharmacological properties. Researchers have explored the scaffold and its derivatives for various therapeutic applications. The unique structure of triazolopyrimidine has made it a valuable template for designing medicinally active molecules. The literature is full of studies showcasing the synthesis and biological activities of compounds containing the triazolopyrimidine ring, either fused or coupled with other heterocycles. The aim of this review is to provide a comprehensive and general summary of the recent advancements in the synthesis of triazolopyrimidine derivatives (Year 2021 to present).

引用

收藏

页码：1567 / 1578

页数：12

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