Nutrition, Vitamin D, and Calcium in Elderly Patients before and after a Hip Fracture and Their Impact on the Musculoskeletal System: A Narrative Review

被引:10
作者
Cianferotti, Luisella [1 ]
Bifolco, Giuseppe [1 ]
Caffarelli, Carla [2 ]
Mazziotti, Gherardo [3 ]
Migliaccio, Silvia [4 ]
Napoli, Nicola [5 ]
Ruggiero, Carmelinda [6 ]
Cipriani, Cristiana [7 ]
机构
[1] Univ Florence, Univ Hosp Florence, Dept Expt & Clin Biomed Sci, Bone Metab Dis Unit, I-50134 Florence, Italy
[2] Univ Siena, Dept Med Surg & Neurosci, Div Internal Med, I-53100 Siena, Italy
[3] Humanitas Univ, IRCCS Humanitas Res Hosp, Dept Biomed Sci, Endocrinol Diabetol & Androl Unit, I-20089 Milan, Italy
[4] Univ Sapienza Rome, Dept Expt Med, I-00185 Rome, Italy
[5] Campus Biomed Rome, Unit Endocrinol & Diabet, Dept Med, I-00128 Rome, Italy
[6] Univ Perugia, Dept Med & Surg, Div Gerontol & Geriatr, Orthogeriatr Unit, I-06156 Perugia, Italy
[7] Sapienza Univ Rome, Dept Clin Internal Anesthesiol & Cardiovasc Sci, I-00185 Rome, Italy
关键词
osteoporosis; fragility fracture; falls; cholecalciferol; calcium carbonate; calcium citrate; calcium intake; DIETARY-PROTEIN INTAKE; D DEFICIENCY; D SUPPLEMENTATION; OLDER-ADULTS; 25-HYDROXYVITAMIN D; POSTMENOPAUSAL WOMEN; HYPOVITAMINOSIS D; BONE TURNOVER; D INADEQUACY; RISK;
D O I
10.3390/nu16111773
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Hip fractures are a major health issue considerably impacting patients' quality of life and well-being. This is particularly evident in elderly subjects, in which the decline in bone and muscle mass coexists and predisposes individuals to fall and fracture. Among interventions to be implemented in hip fractured patients, the assessment and management of nutritional status is pivotal, particularly in subjects older than 65. Nutrition plays a central role in both primary and secondary preventions of fracture. An adequate protein intake improves muscle mass and strength and the intestinal absorption of calcium. Other nutrients with recognized beneficial effects on bone health are calcium, vitamins D, K, and C, potassium, magnesium, folate, and carotenoids. With reference to calcium, results from longitudinal studies showed that the consumption of dairy foods has a protective role against fractures. Moreover, the most recent systematic reviews and meta-analyses and one umbrella review demonstrated that the combination of calcium and vitamin D supplementation significantly reduces hip fracture risk, with presumed higher efficacy in older and institutionalized subjects. Owing to these reasons, the adequate intake of calcium, vitamin D, protein, and other macro and micronutrients has been successfully implemented in the Fracture Liaison Services (FLSs) that represent the most reliable model of management for hip fracture patients. In this narrative review, papers (randomized controlled trials, prospective and intervention studies, and systematic reviews) retrieved by records from three different databases (PubMed, Embase, and Medline) have been analyzed, and the available information on the screening, assessment, and management of nutritional and vitamin D status and calcium intake in patients with hip fractures is presented along with specific prevention and treatment measures.
引用
收藏
页数:18
相关论文
共 34 条
[31]   Association between Vitamin D Deficiency and Prognosis after Hip Fracture Surgery in Older Patients in a Dedicated Orthogeriatric Care Pathway [J].
Dauny, V ;
Thietart, S. ;
Cohen-Bittan, J. ;
Riou, B. ;
Khiami, F. ;
Meziere, A. ;
Verny, M. ;
Boddaert, J. ;
Zerah, L. ;
Villain, C. .
JOURNAL OF NUTRITION HEALTH & AGING, 2022, 26 (04) :324-331
[32]   EFFECTS OF CALCIUM SUPPLEMENTS ON FEMORAL BONE-MINERAL DENSITY AND VERTEBRAL FRACTURE RATE IN VITAMIN-D-REPLETE ELDERLY PATIENTS [J].
CHEVALLEY, T ;
RIZZOLI, R ;
NYDEGGER, V ;
SLOSMAN, D ;
RAPIN, CH ;
MICHEL, JP ;
VASEY, H ;
BONJOUR, JP .
OSTEOPOROSIS INTERNATIONAL, 1994, 4 (05) :245-252
[33]   Changes in alkaline phosphatase, calcium, C-reactive protein, D-dimer, phosphorus and hemoglobin in elderly osteoporotic hip fracture patients [J].
Chen, Zhineng ;
Xie, Lili ;
Xu, Jie ;
Lin, Xiaofang ;
Ye, Juncai ;
Shao, Rongxue ;
Yao, Xinmiao .
ANNALS OF PALLIATIVE MEDICINE, 2021, 10 (02) :1079-1088
[34]   Impact of 3-monthly vitamin D supplementation plus exercise on survival after surgery for osteoporotic hip fracture in adult patients over 50 years: A pragmatic randomized, partially blinded, controlled trial [J].
Ana Laiz ;
J. Malouf ;
A. Marin ;
V. Longobardi ;
J. de Caso ;
J. Farrerons ;
J. Casademont .
The journal of nutrition, health & aging, 2017, 21 :413-420