Zn(II)-catalyzed asymmetric [3+2] cycloaddition of acyclic enones with azomethine ylides

被引：1
|
作者：
Kumar, Sundaravel Vivek [1 ]
Olusegun, Jeremiah [1 ]
Guiry, Patrick J. [1 ]
机构：
[1] Univ Coll Dublin, Ctr Synth & Chem Biol, Sch Chem, Belfield, Dublin, Ireland
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2024年 / 22卷 / 35期
基金：
爱尔兰科学基金会;
关键词：
1,3-DIPOLAR CYCLOADDITION; PYRROLIDINES; INDOLIZIDINE; ALKALOIDS; PROLINE;
D O I：
10.1039/d4ob00854e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The Zn(II)/UCD-Imphanol-catalyzed highly endo-selective [3 + 2] asymmetric cycloaddition of acyclic enones and azomethine ylides has been developed. Moderate to high yields (up to 94%) with excellent endo/exo selectivities (99 : 1) and enantioselectivities up to 96.5 : 3.5 er were obtained.
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页数：7
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