Changing structures, changing paradigms NELF helps regulate paused or elongating RNA polymerase II

被引：0

作者：

Richter, William F. ^{[1
]}

Taatjes, Dylan J. ^{[1
]}

机构：

[1] Univ Colorado, Dept Biochem, Boulder, CO 80303 USA

来源：

MOLECULAR CELL | 2024年 / 84卷 / 07期

关键词：

D O I：

10.1016/j.molcel.2024.03.008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Using cryo-EM and biochemical methods, Su and Vos 1 discover an alternative NELF structural state that enables transcription and switches NELF-RNA polymerase II (RNAPII) compatibility with other RNAPII-associated factors that regulate pausing, elongation, termination, and transcription -coupled DNA repair.

引用

页码：1180 / 1182

页数：3

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