Neurodegenerative Diseases: New Hopes and Perspectives

被引：9

作者：

Bhat, Mohammad Aadil ^{[1
]}

Dhaneshwar, Suneela ^{[2
]}

机构：

[1] Amity Univ Uttar Pradesh, Amity Inst Pharm, Noida, UP, India

[2] Amity Univ Maharashtra, Amity Inst Pharm, Mumbai, Maharashtra, India

来源：

CURRENT MOLECULAR MEDICINE | 2024年 / 24卷 / 08期

关键词：

Alzheimer's disease; Parkinson's disease; Amyotrophic lateral sclerosis; Huntington's disease; Friedrich ataxia; Spinal muscular atrophy; SPINAL MUSCULAR-ATROPHY; TRANSGENIC MOUSE MODEL; AMYOTROPHIC-LATERAL-SCLEROSIS; PLACEBO-CONTROLLED TRIAL; FRONTOTEMPORAL LOBAR DEGENERATION; RECOMBINANT-HUMAN-ERYTHROPOIETIN; MUTANT HUNTINGTIN EXPRESSION; ETHYL-EICOSAPENTAENOIC ACID; STRIATAL CELL-DEATH; DOUBLE-BLIND TRIAL;

D O I：

10.2174/1566524023666230907093451

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Alzheimer's disease, Parkinson's disease, Amyotrophic lateral sclerosis, Huntington's disease, and Friedrich ataxia are all incurable neurodegenerative diseases defined by the continuous progressive loss of distinct neuronal subtypes. Despite their rising prevalence among the world's ageing population, fewer advances have been made in the concurrent massive efforts to develop newer drugs. Recently, there has been a shift in research focus towards the discovery of new therapeutic agents for neurodegenerative diseases. In this review, we have summarized the recently developed therapies and their status in the management of neurodegenerative diseases.

引用

页码：1004 / 1032

页数：29

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