PurposeThe study aims to develop an unsupervised framework using COVGANs to learn better visual representations of COVID-19 from unlabeled X-ray and CT scans.MethodsWe trained multiple-layer GANs to develop the COV-GAN framework on unlabeled X-ray and CT scans. We evaluated the quality of the learned representations using t-SNE visualization, K-means, and GMM clustering. The proposed unsupervised method's performance was compared with leading unsupervised methods for COVID-19 classification on X-ray and CT scans.ResultsOur method achieved an accuracy of 75.1% on X-ray scans and 75.7% on CT scans, which is at least 13.9% and 12.3% higher than the leading unsupervised methods for COVID-19 classification on X-ray and CT scans, respectively. The t-SNE visualization, K-means, and GMM clustering showed that our method learned better visual representations of COVID-19 from unlabeled data.ConclusionsOur unsupervised framework using COV-GANs can learn better visual representations of COVID-19 from unlabeled X-ray and CT scans. The learned representations can improve the performance of COVID-19 classification. The outcomes show the potential of unsupervised learning methods to overcome the dearth of labelled data in the medical profession, particularly in times of public health crises like the COVID-19 epidemic.
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Univ N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USAUniv N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USA
Johnson, Karl
Biddell, Caitlin B. B.
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Univ N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USAUniv N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USA
Biddell, Caitlin B. B.
Hecht, Hillary K. K.
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Univ N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USAUniv N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USA
Hecht, Hillary K. K.
Lich, Kristen H. H.
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Univ N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USAUniv N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USA
Lich, Kristen H. H.
Swann, Julie
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North Carolina State Univ, Dept Ind & Syst Engn, Raleigh, NC USAUniv N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USA
Swann, Julie
Delamater, Paul
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Univ N Carolina, Dept Geog, Chapel Hill, NC 27514 USAUniv N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USA
Delamater, Paul
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Mayorga, Maria
Ivy, Julie
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North Carolina State Univ, Dept Ind & Syst Engn, Raleigh, NC USAUniv N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USA
Ivy, Julie
Smith, Raymond L. L.
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East Carolina Univ, Coll Engn & Technol, Dept Engn, Greenville, NC USAUniv N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USA
Smith, Raymond L. L.
Patel, Mehul D. D.
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Univ N Carolina, Sch Med, Dept Emergency Med, Chapel Hill, NC 27514 USAUniv N Carolina, Gillings Sch Global Publ Hlth, Dept Hlth Policy & Management, Chapel Hill, NC 27514 USA
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Univ Chile, Fac Med, Escuela Salud Publ, Programa Salud Ambiental, Independencia 939, Santiago 8380453, ChileUniv Chile, Fac Med, Escuela Salud Publ, Programa Salud Ambiental, Independencia 939, Santiago 8380453, Chile
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Univ Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Women Global Hlth, Washington, DC 20001 USAUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
van Daalen, Kim Robin
Bajnoczki, Csongor
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WHO, Hlth Syst Governance Collaborat, UHC2030 Alliance, Geneva, SwitzerlandUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Bajnoczki, Csongor
Chowdhury, Maisoon
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Women Global Hlth, Washington, DC 20001 USAUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Chowdhury, Maisoon
Dada, Sara
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Women Global Hlth, Washington, DC 20001 USA
Vayu Global Hlth Fdn, Boston, MA USAUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Dada, Sara
Khorsand, Parnian
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Women Global Hlth, Washington, DC 20001 USAUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Khorsand, Parnian
Socha, Anna
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WHO, Hlth Syst Governance Collaborat, UHC2030 Alliance, Geneva, SwitzerlandUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Socha, Anna
Lal, Arush
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Women Global Hlth, Washington, DC 20001 USAUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Lal, Arush
Jung, Laura
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Women Global Hlth, Washington, DC 20001 USA
Univ Leipzig, Leipzig, GermanyUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Jung, Laura
Alqodmani, Lujain
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Educ & Agr Together EAT Fdn, Oslo, NorwayUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Alqodmani, Lujain
Torres, Irene
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Fdn Octaedro, Quito, EcuadorUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
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Women Global Hlth, Garowe, Somalia
Uppsala Univ, Dept Int Maternal & Child Hlth, Dept Womens & Childrens Hlth, Uppsala, SwedenUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Mahmud, Amina Jama
Dhatt, Roopa
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Women Global Hlth, Washington, DC 20001 USAUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Dhatt, Roopa
Phelan, Alexandra
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Georgetown Univ, Ctr Global Hlth Sci & Secur, Washington, DC USAUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England
Phelan, Alexandra
Rajan, Dheepa
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WHO, Hlth Syst Governance Collaborat, UHC2030 Alliance, Geneva, SwitzerlandUniv Cambridge, Cardiovasc Epidemiol Unit, Cambridge, England