Electrical Stimulation and Motor Function Rehabilitation in Spinal Cord Injury: A Systematic Review

被引：1
作者：
Kanakis, Asterios K. [1 ]
Benetos, Ioannis S. [2 ]
Evangelopoulos, Dimitrios Stergios [2 ]
Vlamis, John [2 ]
Vasiliadis, Elias S. [2 ]
Kotroni, Aikaterini [1 ]
Pneumaticos, Spyros G. [2 ]
机构：
[1] KAT Hosp, Dept Phys Med & Rehabil, Athens, Greece
[2] Natl & Kapodistrian Univ Athens NKUA, KAT Hosp, Dept Orthopaed Surg 3, Athens, Greece
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 05期
关键词：
motor recovery; function; functional electrical stimulation (fes); transcutaneous spinal cord stimulation (tscs); epidural spinal cord stimulation (escs); electrical stimulation; spinal cord stimulation; spinal cord injury; LUMBAR CORD; EPIDURAL STIMULATION; HAND FUNCTION; MUSCLE; WALKING; MODULATION; MOVEMENTS; RECOVERY; NEUROMODULATION; RESPONSES;
D O I：
10.7759/cureus.61436
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Spinal cord injury (SCI) often leads to devastating motor impairments, significantly affecting the quality of life of affected individuals. Over the last decades, spinal cord electrical stimulation seems to have encouraging effects on the motor recovery of impacted patients. This review aimed to identify clinical trials focused on motor function recovery through the application of epidural electrical stimulation, transcutaneous electrical stimulation, and functional electrical stimulation. Several clinical trials met these criteria, focusing on the impact of the aforementioned interventions on walking, standing, swimming, trunk stability, and upper extremity functionality, particularly grasp. After a thorough PubMed online database research, 37 clinical trials were included in this review, with a total of 192 patients. Many of them appeared to have an improvement in function, either clinically assessed or recorded through electromyography. This review outlines the various ways electrical stimulation techniques can aid in the motor recovery of SCI patients. It stresses the ongoing need for medical research to refine these techniques and ultimately enhance rehabilitation results in clinical settings.
引用
收藏
页数：12
相关论文
共 60 条
[1]   Restoration of reaching and grasping movements through brain-controlled muscle stimulation in a person with tetraplegia: a proof-of-concept demonstration [J].
Ajiboye, A. Bolu ;
Willett, Francis R. ;
Young, Daniel R. ;
Memberg, William D. ;
Murphy, Brian A. ;
Miller, Jonathan P. ;
Walter, Benjamin L. ;
Sweet, Jennifer A. ;
Hoyen, Harry A. ;
Keith, Michael W. ;
Peckham, P. Hunter ;
Simeral, John D. ;
Donoghue, John P. ;
Hochberg, Leigh R. ;
Kirsch, Robert F. .
LANCET, 2017, 389 (10081) :1821-1830
[2]   Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms [J].
Alizadeh, Arsalan ;
Dyck, Scott Matthew ;
Karimi-Abdolrezaee, Soheila .
FRONTIERS IN NEUROLOGY, 2019, 10
[3]   Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans [J].
Angeli, Claudia A. ;
Edgerton, V. Reggie ;
Gerasimenko, Yury P. ;
Harkema, Susan J. .
BRAIN, 2014, 137 :1394-1409
[4]   Spinal Cord Injury: Pathophysiology, Multimolecular Interactions, and Underlying Recovery Mechanisms [J].
Anjum, Anam ;
Yazid, Muhammad Da'in ;
Fauzi Daud, Muhammad ;
Idris, Jalilah ;
Ng, Angela Min Hwei ;
Selvi Naicker, Amaramalar ;
Ismail, Ohnmar Htwe Rashidah ;
Athi Kumar, Ramesh Kumar ;
Lokanathan, Yogeswaran .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (20) :1-35
[5]  
[Anonymous], 2016, J Spinal Cord Med, V39, P493, DOI 10.1080/10790268.2016.1210925
[6]   Electrophysiological Guidance of Epidural Electrode Array Implantation over the Human Lumbosacral Spinal Cord to Enable Motor Function after Chronic Paralysis [J].
Calvert, Jonathan S. ;
Grahn, Peter J. ;
Strommen, Jeffrey A. ;
Lavrov, Igor A. ;
Beck, Lisa A. ;
Gill, Megan L. ;
Linde, Margaux B. ;
Brown, Desmond A. ;
Van Straaten, Meegan G. ;
Veith, Daniel D. ;
Lopez, Cesar ;
Sayenko, Dimitry G. ;
Gerasimenko, Yury P. ;
Edgerton, V. Reggie ;
Zhao, Kristin D. ;
Lee, Kendall H. .
JOURNAL OF NEUROTRAUMA, 2019, 36 (09) :1451-1460
[7]   Epidural spinal-cord stimulation facilitates recovery of functional walking following incomplete spinal-cord injury [J].
Carhart, MR ;
He, JP ;
Herman, R ;
D'Luzansky, S ;
Willis, WT .
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 2004, 12 (01) :32-42
[8]   Activating effective functional hand movements in individuals with complete tetraplegia through neural stimulation [J].
Coste, Christine Azevedo ;
William, Lucie ;
Fonseca, Lucas ;
Hiairrassary, Arthur ;
Andreu, David ;
Geffrier, Antoine ;
Teissier, Jacques ;
Fattal, Charles ;
Guiraud, David .
SCIENTIFIC REPORTS, 2022, 12 (01)
[9]   Modulation of multisegmentalmonosynaptic responses in a variety of leg muscles during walking and running in humans [J].
Courtine, Gr Goire ;
Harkema, Susan J. ;
Dy, Christine J. ;
Gerasimenko, Yuri P. ;
Dyhre-Poulsen, Poul .
JOURNAL OF PHYSIOLOGY-LONDON, 2007, 582 (03) :1125-1139
[10]   Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury [J].
Courtine, Gregoire ;
Song, Bingbing ;
Roy, Roland R. ;
Zhong, Hui ;
Herrmann, Julia E. ;
Ao, Yan ;
Qi, Jingwei ;
Edgerton, V. Reggie ;
Sofroniew, Michael V. .
NATURE MEDICINE, 2008, 14 (01) :69-74
123456