Advances in Iron Deficiency Anaemia Management: Exploring Novel Drug Delivery Systems and Future Perspectives

被引:3
作者
Saini, Muskan [1 ]
Trehan, Karan [1 ]
Thakur, Shubham [1 ]
Modi, Anuj [2 ]
Jain, Subheet Kumar [1 ]
机构
[1] Guru Nanak Dev Univ, Dept Pharmaceut Sci, Amritsar 143005, India
[2] Delhi Skill & Entrepreneurship Univ, Dept Pharm, Dwarka Campus, New Delhi 110077, India
关键词
Iron deficiency anaemia; novel drug delivery systems; etiology; diagnosis; management; HEART-FAILURE; INTRAVENOUS IRON; DIAGNOSIS; HEPCIDIN; NANOPARTICLES; STRATEGIES; FERRITIN; DISEASE; RATS; CKD;
D O I
10.2174/0115672018300804240426070552
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Iron Deficiency Anaemia (IDA) is a prevalent global health issue characterized by inadequate iron levels in the body, leading to impaired red blood cell production and subsequent anaemia. Traditional treatment approaches for IDA, such as oral iron supplementation, often encounter challenges related to poor compliance, gastrointestinal side effects, and variable absorption rates. As a result, there is a growing interest in exploring novel drug delivery systems to enhance iron therapy efficacy and patient outcomes. This review discusses recent advances in IDA management, focusing on developing and utilizing innovative drug delivery systems for iron supplementation. Various strategies, including nanoformulations, microparticles, liposomes, and hydrogels, are explored for their potential to improve iron bioavailability, reduce adverse effects, and optimize therapeutic outcomes. Furthermore, promising strategies for the future management of IDA are explored, including the utilization of advanced technologies such as targeted drug delivery systems, controlled release mechanisms, and combination therapies. The integration of these novel drug delivery systems with advancements in diagnostics, personalized medicine, and patient-centered care holds great potential to revolutionize the management of IDA and improve the quality of life for individuals affected by this condition.
引用
收藏
页码:493 / 509
页数:17
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