Current Status and Perspectives of Diagnosis and Treatment of Periprosthetic Joint Infection

被引：11

作者：

Zhou, Haotian ^{[1
,2
]}

Yang, Yaji ^{[1
,2
]}

Zhang, Yanhao ^{[3
]}

Li, Feilong ^{[1
,2
]}

Shen, Yidong ^{[4
]}

Qin, Leilei ^{[1
,2
]}

Huang, Wei ^{[1
,2
]}

机构：

[1] Chongqing Med Univ, Affiliated Hosp 1, Dept Orthopaed, Chongqing 400016, Peoples R China

[2] Chongqing Med Univ, Orthoped Lab, Chongqing 400016, Peoples R China

[3] Army Mil Med Univ, Coll Pharm, Coll Pharm, Chongqing 400038, Peoples R China

[4] First Peoples Hosp Yancheng, Dept Orthopaed, Yancheng, Peoples R China

来源：

INFECTION AND DRUG RESISTANCE | 2024年 / 17卷

关键词：

arthroplasty; periprosthetic joint infection; PJI; molecular diagnosis; pathogenesis diagnosis; antibiotic application; recurrence of infection; SYNOVIAL-FLUID BIOMARKERS; SERUM D-DIMER; ONE-STAGE; MSIS CRITERIA; MULTIPLEX PCR; KNEE; HIP; ARTHROPLASTY; SONICATION; REVISION;

D O I：

10.2147/IDR.S457644

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Periprosthetic joint infection (PJI) is a catastrophic complication following joint replacement surgery, posing significant challenges to orthopedic surgeons. Due to the lack of a definitive diagnostic gold standard, timely treatment initiation is problematic, resulting in substantial economic burdens on patients and society. In this review, we thoroughly analyze the complexities of PJI and emphasize the importance of accurate diagnosis and effective treatment. The article specifically focuses on the advancements in diagnostic techniques, ranging from traditional pathogen culture to advanced molecular diagnostics, and discusses their role in enhancing diagnostic accuracy. Additionally, we review the latest surgical management strategies, including everything from debridement to revision surgeries. Our summary aims to provide practical information for the diagnosis and treatment of PJI and encourages further research to improve diagnostic accuracy and treatment outcomes.

引用

页码：2417 / 2429

页数：13

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