Endotoxins in Household Dust in Northern China: Associations with Home Environment Factors and Childhood Asthma and Allergies

被引：1

作者：

Zhao, Yuxuan ^{[1
]}

Liu, Yixin ^{[1
]}

Cui, Lianwang ^{[1
]}

Hou, Jing ^{[1
]}

Gao, Feng ^{[2
]}

Norback, Dan ^{[3
]}

Sun, Yuexia ^{[1
]}

机构：

[1] Tianjin Univ, Sch Environm Sci & Engn, Tianjin Key Lab Indoor Air Environm Qual Control, Tianjin 300350, Peoples R China

[2] Tianjin Architecture Design Inst Co Ltd, Tianjin 300350, Peoples R China

[3] Uppsala Univ, Dept Med Sci, S-75105 Uppsala, Sweden

来源：

ATMOSPHERE | 2024年 / 15卷 / 07期

基金：

中国国家自然科学基金;

关键词：

allergic symptoms; building characteristics; endotoxin; indoor environment; MATTRESS DUST; RISK-FACTOR; DETERMINANTS; EXPOSURE; PREVALENCE; PREDICTORS; SYMPTOMS; WHEEZE; ISAAC;

D O I：

10.3390/atmos15070759

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The available information on endotoxin in Chinese households is limited and there is inconsistency regarding its impact on asthma and allergies in children. A case-control study was performed in 324 homes in Tianjin, China. Linear regression analysis was performed to identify the determinants of endotoxin concentrations in household dust. Logistic regression models were employed to investigate the associations of endotoxin concentrations with asthma and allergies in children. Endotoxin concentrations were determined from 284 valid dust samples, ranging from 94 to 11,625 EU/g, with a mean concentration of 3638 EU/g. We found a significant positive association between endotoxin concentrations and children's current asthma. Old houses, ventilation systems without exhaust fans and windows opened infrequently were related to higher concentrations of endotoxins. In conclusion, endotoxin exposure in the home might be a risk factor for current asthma in children. Strategies for controlling endotoxin concentrations such as building maintenance and ventilation improvements are recommended.

引用

页数：11

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