Nano-Revolution in Transdermal Drug Delivery: A Bibliographic Compilation of Vesicular System

Background: The growing popularity of transdermal patches is attributed to their advantageous characteristics, including the absence of gastric-related problems, prolonged drug release, enhanced safety and stability, and the elimination of the need for punctures during systemic delivery. These features have prompted the exploration of novel techniques and innovations in transdermal delivery systems to optimize drug administration. Materials and Methods: To address the aforementioned advantages, researchers have focused on incorporating innovative approaches, with a particular emphasis on the utilization of nano-vesicular systems. The nano-vesicular system has gained favour due to its potential to significantly increase drug accumulation at the site of administration, its capacity to easily incorporate a wide range of medications, and its ability to minimize systemic drug absorption. This study undertook an examination of the attempts made in the development and implementation of transdermal nano-vesicular administration. Results: This study revealed the successful adoption and application of nano-vesicular systems in transdermal drug delivery. The results highlight the efficacy of this approach in enhancing drug accumulation at the administration site and its versatility in accommodating various medications. Additionally, the observed low systemic drug absorption further underscores the potential benefits of transdermal nano-vesicular administration. Conclusion: In conclusion, the study demonstrates the increasing significance of transdermal patches and the promising role played by nano-vesicular systems in addressing key challenges associated with systemic drug delivery. The successful examination of transdermal nano-vesicular administration by the authors emphasizes the advancements in this field and encourages further exploration of its potential applications in pharmaceutical delivery systems.