Ultrasound evaluation and grading of neuromuscular disease in lower extremities among diabetic patients

被引:1
|
作者
Jiang, Wenting [1 ]
Liao, Liping [1 ]
Lai, Zhenhan [1 ]
Li, Kaiwu [1 ]
Luo, Weiwen [1 ]
Shen, Haolin [2 ]
机构
[1] Fujian Med Univ, Zhangzhou Affiliated Hosp, Dept Ultrasound, Zhangzhou 363000, Fujian, Peoples R China
[2] Fujian Med Univ, Zhangzhou Affiliated Hosp, Sci & Educ Sect, 59 Shengli Rd, Zhangzhou 363000, Fujian, Peoples R China
来源
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH | 2024年 / 16卷 / 07期
关键词
Ultrasound; diabetes mellitus; neuromuscular disease of the lower extremity; common peroneal nerve; PERIPHERAL NEUROPATHY; NERVES;
D O I
10.62347/WNSL1894
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objective: To explore the clinical utility of ultrasound in evaluating and grading neuromuscular diseases in the lower extremities of patients with diabetes mellitus. Methods: A total of 126 inpatients from the Department of Diabetes at Zhangzhou Affiliated Hospital of Fujian Medical University, China, were recruited from June 2020 to December 2022. The cohort included 69 patients with type 2 diabetes mellitus (T2DM) and diabetic peripheral neuropathy (DPN group) and 57 patients with T2DM but without DPN (non-DPN group). Additionally, 80 healthy controls were included. High-frequency ultrasound was used to scan the common peroneal, sural, and tibial nerves, measuring their transverse (D1) and anteroposterior (D2) diameters, and calculating the cross-sectional area (CSA). Changes in the internal echo of the extensor digitorum brevis (EDB) muscle, including maximum thickness and CSA, were also recorded. The DPN group was further subdivided based on disease duration to assess ultrasonic changes over time and the statistical significance of these variations. Results: Ultrasonic changes such as uneven internal echo reduction, ill-defined epineurial boundaries, and obscured cribriform structures were most prevalent in the DPN group. Significant differences in ultrasound parameters (D1, D2, CSA) were observed among the groups (all P<0.05), with the most pronounced changes in the DPN group. In patients with a disease duration of over 15 years, a significant increase in CSA of lower extremity nerves and a decrease in CSA of the EDB were noted compared to those in the 5-10 years subgroup (19.89 +/- 0.98 vs 19.00 +/- 0.94; 5.25 +/- 0.74 vs 5.93 +/- 0.94; all P<0.05). Conclusions: High-frequency ultrasound provides a valuable imaging basis for diagnosing and monitoring DPN, demonstrating significant changes in nerve and muscle parameters among diabetic patients.
引用
收藏
页码:3280 / 3288
页数:9
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