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Downbeat nystagmus: a clinical and pathophysiological review
被引:0
|作者:
Marcelli, Vincenzo
[1
,2
]
Giannoni, Beatrice
[3
]
Volpe, Giampiero
[4
]
Faralli, Mario
[5
,6
]
Fetoni, Anna Rita
[2
]
Pettorossi, Vito E.
[6
]
机构:
[1] Osped Mare, ASL Napoli Ctr 1, Dept ENT, Audiol & Vestibol Unit, Naples, Italy
[2] Univ Naples Federico II, Dept Neurosci Reprod Sci & Dent, Sect Audiol, Naples, Italy
[3] Univ Florence, Dept Neurosci Psychol Drugs Area & Childs Hlth, Florence, Italy
[4] Osped San Luca Vallo Lucania, Dept Neurol, ASL Salerno, Salerno, Italy
[5] Univ Perugia, Dept ENT, Perugia, Italy
[6] Univ Perugia, Dept Med & Surg, Perugia, Italy
来源:
FRONTIERS IN NEUROLOGY
|
2024年
/
15卷
关键词:
downbeat nystagmus;
downbeat nystagmus syndrome;
vertical reflex asymmetry;
neural integrator;
central neurological disorders;
VERTICAL OPTOKINETIC NYSTAGMUS;
CHIARI-I MALFORMATION;
PARANEOPLASTIC CEREBELLAR DEGENERATION;
FAMILIAL HEMIPLEGIC MIGRAINE;
SIMPLE-SPIKE ACTIVITY;
VESTIBULOOCULAR REFLEX;
EYE-MOVEMENTS;
SPINOCEREBELLAR-ATAXIA;
POSITIONAL VERTIGO;
PURKINJE-CELLS;
D O I:
10.3389/fneur.2024.1394859
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Downbeat nystagmus (DBN) is a neuro-otological finding frequently encountered by clinicians dealing with patients with vertigo. Since DBN is a finding that should be understood because of central vestibular dysfunction, it is necessary to know how to frame it promptly to suggest the correct diagnostic-therapeutic pathway to the patient. As knowledge of its pathophysiology has progressed, the importance of this clinical sign has been increasingly understood. At the same time, clinical diagnostic knowledge has increased, and it has been recognized that this sign may occur sporadically or in association with others within defined clinical syndromes. Thus, in many cases, different therapeutic solutions have become possible. In our work, we have attempted to systematize current knowledge about the origin of this finding, the clinical presentation and current treatment options, to provide an overview that can be used at different levels, from the general practitioner to the specialist neurologist or neurotologist.
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页数:16
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