Association between coffee and caffeine intake and risk of COPD: Findings based on NHANES 2007-2012

被引：2

作者：

Liao, Wan-Zhe ^{[1
,2
]}

Li, Jia-Xin ^{[1
,2
]}

Feng, Wei-Yi ^{[1
,2
]}

Xiao, Jia-Qi ^{[1
,2
]}

Wang, Zi-Xun ^{[1
,2
]}

Xie, Shuo-Jia ^{[1
]}

Hu, Yi-Ming ^{[4
]}

Mao, Jun-Hao ^{[5
]}

Huang, Ze-Min ^{[2
,3
]}

Guo, Xu-Guang ^{[2
,3
,6
,7
]}

Guan, Wei-Jie ^{[1
,8
]}

机构：

[1] Guangzhou Med Univ, Affiliated Hosp 1, Guangzhou Inst Resp Hlth, Natl Clin Res Ctr Resp Dis, Guangzhou, Peoples R China

[2] Guangzhou Med Univ, Guangdong Prov Clin Res Ctr Obstet & Gynecol, Guangdong Prov Key Lab Major Obstet Dis, Dept Clin Lab Med,Affiliated Hosp 3, Guangzhou 510150, Peoples R China

[3] Guangzhou Med Univ, Clin Sch 3, Dept Clin Med, Guangzhou 511436, Peoples R China

[4] Univ Elect Sci & Technol, Glasgow Coll, Dept Elect Informat Engn, Chengdu 611731, Peoples R China

[5] Nanjing Univ Posts & Telecommun, Dept Comp Sci, Nanjing 210023, Peoples R China

[6] Guangzhou Med Univ, King Med Sch Lab Med, Guangzhou Key Lab Clin Rapid Diag & Early Warning, Guangzhou 510000, Peoples R China

[7] Guangzhou Med Univ, Affiliated Hosp 3, Dept Clin Lab Med, Guangzhou, Peoples R China

[8] Guangzhou Med Univ, Affiliated Hosp 1, Natl Clin Res Ctr Resp Dis, Guangzhou, Peoples R China

来源：

HEART & LUNG | 2024年 / 67卷

关键词：

Coffee; Caffeine; COPD; Cross-sectional study; NHANES; OBSTRUCTIVE PULMONARY-DISEASE; CONSUMPTION; PREVALENCE; BENEFITS; SMOKING; SAFETY; BURDEN; HEALTH;

D O I：

10.1016/j.hrtlng.2024.04.015

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: The association between coffee and caffeine intake and the risk of COPD and lung function has not been thoroughly discussed in Americans, with subgroup and threshold effects remaining unclear. Objectives: This study investigated the association between coffee and caffeine consumption and the risk of chronic obstructive pulmonary disease (COPD) as well as lung function utilizing data from the NHANES 2007-2012. Methods: We assessed the associations of coffee and caffeine consumption with the risk of COPD and lung function parameters, including FEV1 and FVC, adjusting for common demographic and disease characteristics in a cross-sectional analysis of NHANES data. Results: A total of 9763 participants were included in the study, and 592 were diagnosed with COPD. Multivariate regression models revealed positive associations between coffee and caffeine consumption and the risk of COPD and lung function. Subgroup analyses stratified by sex, DM, hypertension status, and smoking habits identified potential effect modifiers as well as inflection points from threshold effect examinations. Conclusions: The results of this cross-sectional study indicated significant positive correlations between coffee and caffeine consumption and the risk of COPD. Additionally, positive correlations between exposure variables and FEV1 and FVC were detected. Among the stratification factors, smoking status exhibited the most potential for modifying effects. Future practices and research are needed to validate the results and explore the underlying mechanisms

引用

页码：53 / 61

页数：9