Novel 2,7-Naphthyridine Compounds as MASTL Inhibitors for Treating Cancer

被引：0
|
作者：
Sabnis, Ram W. [1 ]
机构：
[1] Gambrell & Russell LLP, Smith, Atlanta, GA 30309 USA
来源：
ACS MEDICINAL CHEMISTRY LETTERS | 2024年 / 15卷 / 06期
关键词：
D O I：
10.1021/acsmedchemlett.4c00177
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Provided herein are novel 2,7-naphthyridine compounds as MASTL inhibitors, pharmaceutical compositions, use of such compounds in treating cancer, and processes for preparing such compounds.
引用
收藏
页码：748 / 749
页数：2
相关论文
共 50 条
  • [11] ALKYLENEIMIDES .7. A NEW SYNTHESIS OF 2,7-NAPHTHYRIDINE DERIVATIVES
    ISELIN, BM
    HOFFMANN, K
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1954, 76 (12) : 3220 - 3222
  • [12] First total synthesis of the 2,7-naphthyridine alkaloids lophocladine A and B
    Lotter, Matthias
    Schilling, Johannes
    Reimann, Eberhard
    Bracher, Franz
    ARCHIV DER PHARMAZIE, 2006, 339 (12) : 677 - 679
  • [13] 1,7-and 2,7-naphthyridine derivatives as potent and highly specific PDE5 inhibitors
    Ukita, T
    Nakamura, Y
    Kubo, A
    Yamamoto, Y
    Moritani, Y
    Saruta, K
    Higashijima, T
    Kotera, J
    Fujishige, K
    Takagi, M
    Kikkawa, K
    Omori, K
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (14) : 2341 - 2345
  • [14] NETEROCYCLES FROM AMINO KETONES .18. SYNTHESIS OF 2,7-NAPHTHYRIDINE
    KEMPTER, G
    KLUG, P
    ZEITSCHRIFT FUR CHEMIE, 1971, 11 (02): : 61 - &
  • [15] Novel Compounds as CDK2 Inhibitors for Treating Cancer
    Sabnis, Ram W.
    ACS MEDICINAL CHEMISTRY LETTERS, 2024, 16 (01): : 14 - 15
  • [16] Synthesis of furo[2,3-c]-2,7-naphthyridine derivatives via domino heterocyclization reaction
    Tverdokhlebov, AV
    Zavada, AV
    Tolmachev, AA
    Kostyuk, AN
    Chernega, AN
    Rusanov, EB
    TETRAHEDRON, 2005, 61 (40) : 9618 - 9623
  • [17] Synthesis of new pentaheterocyclic systems based on the triazolo[3,4-a]-2,7-naphthyridine core
    Sirakanyan, Samvel N.
    Spinelli, Domenico
    Geronikaki, Athina
    Hakobyan, Elmira K.
    Kartsev, Victor G.
    Yegoryan, Hasmik A.
    Paronikyan, Ervand G.
    Ghazaryan, Samvel G.
    Hovakimyan, Anush A.
    ARKIVOC, 2022, : 1 - 10
  • [18] An efficient synthesis of dibenzo[c,f]-2,7-naphthyridine ring system through design of experiments
    Gopalsamy, Ariamala
    Shi, Mengxiao
    Nilakantan, Ramaswamy
    ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2007, 11 (03) : 450 - 454
  • [19] FIRST TOTAL SYNTHESIS OF THE 2,7-NAPHTHYRIDINE ALKALOID NEOZEYLANICINE AND UNEXPECTED FORMATION OF ISOQUINOLINES FROM ETHOXYVINYL PYRIDINES
    BRACHER, F
    MINK, K
    LIEBIGS ANNALEN, 1995, (04): : 645 - 647
  • [20] AMINATION OF 2,6-NAPHTHYRIDINE AND 2,7-NAPHTHYRIDINE - AN NMR-STUDY ON OMEGA-ADDUCTS OF HETEROCYCLIC-SYSTEMS WITH AMIDE IONS
    VANDENHAAK, HJW
    VANDERPLAS, HC
    VANVELDHUIZEN, B
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1981, 18 (07) : 1349 - 1352
12345