Association between the severity of hypothermia and in-hospital mortality in patients with infectious diseases: The J-Point registry

被引：0

作者：

Shiozumi, Tadaharu ^{[1
]}

Miyamoto, Yuki ^{[1
]}

Morita, Sachiko ^{[2
]}

Ehara, Naoki ^{[3
]}

Miyamae, Nobuhiro ^{[4
]}

Okada, Yohei ^{[5
,6
]}

Jo, Takaaki ^{[7
]}

Sumida, Yasuyuki ^{[4
,8
]}

Okada, Nobunaga ^{[1
,3
,9
]}

Watanabe, Makoto ^{[1
]}

Nozawa, Masahiro ^{[10
,11
]}

Tsuruoka, Ayumu ^{[12
,13
]}

Fujimoto, Yoshihiro ^{[14
]}

Okumura, Yoshiki ^{[15
]}

Kitamura, Tetsuhisa ^{[16
]}

Matsuyama, Tasuku ^{[1
]}

机构：

[1] Kyoto Prefectural Univ Med, Dept Emergency Med, Kamigyo Ku, Kyoto 6028566, Japan

[2] Saiseikai Senri Hosp, Senri Crit Care Med Ctr, Dept Emergency & Crit Care Med, Suita, Japan

[3] Japanese Red Cross Kyoto Daiichi Hosp, Dept Emergency Med, Kyoto, Japan

[4] Rakuwa Kai Otowa Hosp, Dept Emergency Med, Kyoto, Japan

[5] Japanese Red Cross Soc Kyoto Daini Red Cross Hosp, Dept Emergency & Crit Care Med, Kyoto, Japan

[6] Natl Univ Singapore, Duke NUS Med Sch, Hlth Serv & Syst Res, Singapore City, Singapore

[7] Uji Tokushukai Med Ctr, Dept Emergency Med, Uji, Japan

[8] Kyoto Prefectural Univ Med, North Med Ctr, Dept Emergency Med, Yosa, Japan

[9] Kyoto Med Ctr, Natl Hosp Org, Dept Emergency & Crit Care Med, Kyoto, Japan

[10] Saiseikai Shiga Hosp, Dept Emergency & Crit Care Med, Ritto, Japan

[11] Shiga Gen Hosp, Dept Emergency Med, Moriyama, Japan

[12] Kyoto Min Iren Chuo Hosp, Kidney & Cardiovasc Ctr, Dept Emergency & Crit Care Med, Kyoto, Japan

[13] Osaka City Gen Hosp, Emergency & Crit Care Med Ctr, Dept Emergency & Crit Care Med, Osaka, Japan

[14] Yodogawa Christians Hosp, Dept Emergency Med, Osaka, Japan

[15] Fukuchiyama City Hosp, Dept Emergency Med, Fukuchiyama, Japan

[16] Osaka Univ, Grad Sch Med, Dept Social & Environm Med, Div Environm Med & Populat Sci, Suita, Japan

来源：

ACUTE MEDICINE & SURGERY | 2024年 / 11卷 / 01期

关键词：

accidental hypothermia; emergency department; environmental medicine; infection; mortality; ACCIDENTAL HYPOTHERMIA; MILD HYPOTHERMIA; RAT MODEL; SEPSIS; GUIDELINES; RESPONSES; FEVER;

D O I：

10.1002/ams2.964

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim: Hypothermia is associated with poor prognosis in patients with sepsis. However, no studies have explored the correlation between the severity of hypothermia and prognosis. Methods: Using data from the Japanese accidental hypothermia network registry (J-Point registry), we examined adult patients aged >= 18 years with infectious diseases whose initial body temperature was <= 35 degrees C from April 1, 2011 to March 31, 2016, in 12 centers. Patients were divided into three groups according to their body temperature: Tertile 1 (T1) (32.0-35.0 degrees C), Tertile 2 (T2) (28.0-31.9 degrees C), and Tertile 3 (T3) (<28.0 degrees C). In-hospital mortality was employed as a metric to assess outcomes. We conducted a multivariate logistic regression analysis to investigate the relationship between the three categories and the occurrence of in-hospital mortality. Results: A total of 572 patients were registered, and 170 eligible patients were identified. Of these patients, 55 were in T1 (32.0-35.0 degrees C), 76 in T2 (28.0-31.9 degrees C), and 39 in T3 (<28.0 degrees C) groups. The overall in-hospital mortality rate in accidental hypothermia (AH) patients with infectious diseases was 34.1%. The in-hospital mortality rates in the T1, T2, and T3 groups were 34.5%, 36.8%, and 28.2%, respectively. The multivariable analysis demonstrated no significant differences regarding in-hospital mortality among the three groups (T2 vs. T1, adjusted odds ratio [OR]: 1.29; 95% confidence interval [CI]: 0.58-2.89 and T3 vs. T1, adjusted OR: 0.83; 95% CI: 0.30-2.31). Conclusion: In this multicenter retrospective observational study, hypothermia severity was not associated with in-hospital mortality in AH patients with infectious diseases.

引用

页数：9

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