Quantum Dot Research in Breast Cancer: Challenges and Prospects

被引:11
作者
Omidian, Hossein [1 ]
Wilson, Renae L. [1 ]
Cubeddu, Luigi X. [1 ]
机构
[1] Nova Southeastern Univ, Barry & Judy Silverman Coll Pharm, Ft Lauderdale, FL 33328 USA
关键词
quantum dots; breast cancer; targeted therapy; nanomedicine; personalized medicine; GROWTH-FACTOR RECEPTOR; PROGNOSTIC VALUE; ULTRASENSITIVE DETECTION; QUANTITATIVE-ANALYSIS; HER2; EXPRESSION; DOWN-REGULATION; COLLAGEN-IV; CELL; ANTIBODY; NANOPARTICLES;
D O I
10.3390/ma17092152
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The multifaceted role of quantum dots (QDs) in breast cancer research highlights significant advancements in diagnostics, targeted therapy, and drug delivery systems. This comprehensive review addresses the development of precise imaging techniques for early cancer detection and the use of QDs in enhancing the specificity of therapeutic delivery, particularly in challenging cases like triple-negative breast cancer (TNBC). The paper also discusses the critical understanding of QDs' interactions with cancer cells, offering insights into their potential for inducing cytotoxic effects and facilitating gene therapy. Limitations such as biocompatibility, toxicity concerns, and the transition from laboratory to clinical practice are critically analyzed. Future directions emphasize safer, non-toxic QD development, improved targeting mechanisms, and the integration of QDs into personalized medicine, aiming to overcome the current challenges and enhance breast cancer management.
引用
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页数:40
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