Psychological symptoms and health-related quality of life in intubated and non-intubated intensive care survivors: A multicentre, prospective observational cohort study

被引：2

作者：

Rai, Sumeet ^{[1
,2
]}

Neeman, Teresa ^{[3
]}

Brown, Rhonda ^{[4
,5
]}

Sundararajan, Krishnaswamy ^{[6
,7
]}

Rajamani, Arvind ^{[8
,9
]}

Miu, Michelle ^{[10
]}

Panwar, Rakshit ^{[11
]}

Nourse, Mary ^{[2
]}

Haren, Frank M. P. van ^{[1
,12
]}

Mitchell, Imogen ^{[1
,2
]}

Needham, Dale M. ^{[13
,14
,15
]}

机构：

[1] Australian Natl Univ, Sch Med & Psychol, Canberra, Australia

[2] Canberra Hosp, Intens Care Unit, Canberra, Australia

[3] Australian Natl Univ, Biol Data Sci Inst, Coll Sci, Canberra, Australia

[4] Australian Natl Univ, Res Sch Psychol, Canberra, Australia

[5] Univ New England, Sch Psychol, Armidale, NSW, Australia

[6] Royal Adelaide Hosp, Intens Care Unit, Adelaide, Australia

[7] Univ Adelaide, Fac Hlth & Med Sci, Adelaide, Australia

[8] Univ Sydney, Nepean Clin Sch, Sydney, Australia

[9] Nepean Hosp, Intens Care Unit, Sydney, Australia

[10] Nepean Hosp, Sydney, Australia

[11] John Hunter Hosp, Intens Care Unit, New Lambton, Australia

[12] St George Hosp, Intens Care Unit, Sydney, Australia

[13] Johns Hopkins Univ Hosp, Crit Care Phys Med & Rehabil Program, Baltimore, MD USA

[14] Johns Hopkins Univ, Sch Med, Baltimore, MD USA

[15] Johns Hopkins Univ, Sch Nursing, Baltimore, MD USA

来源：

CRITICAL CARE AND RESUSCITATION | 2024年 / 26卷 / 01期

关键词：

Intensive care; Survivorship; Psychology; Quality of life; POSTTRAUMATIC-STRESS-DISORDER; LONG-TERM OUTCOMES; CRITICAL ILLNESS; NONINVASIVE VENTILATION; UNIT SURVIVORS; FOLLOW-UP; ASSOCIATION; CHALLENGES; DEPRESSION; CANCER;

D O I：

10.1016/j.ccrj.2023.10.011

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Objective: To compare long-term psychological symptoms and health-related quality of life (HRQOL) in intubated versus non-intubated ICU survivors. Design: Prospective, multicentre observational cohort study. Setting: Four tertiary medical-surgical ICUs in Australia. Participants: Intubated and non-intubated adult ICU survivors. Main outcome measures: Primary outcomes: clinically significant psychological symptoms at 3- and 12-month follow-up using Post-Traumatic Stress Syndrome-14 for post-traumatic stress disorder; Depression, Anxiety Stress Scales-21 for depression, anxiety, and stress. Secondary outcomes: HRQOL, using EuroQol-5D-5L questionnaire. Results: Of the 133 ICU survivors, 54/116 (47 %) had at least one clinically significant psychological symptom (i.e., post-traumatic stress disorder, anxiety, depression, stress) at follow-up. Clinically significant scores for psychological symptoms were observed in 26 (39 %) versus 16 (32 %) at 3-months [odds ratio 1.4, 95 % confidence interval (0.66-3.13), p = 0.38]; 23 (37 %) versus 10 (31 %) at 12-months [odds ratio 1.3, 95 % confidence interval (0.53-3.31), p = 0.57] of intubated versus non-intubated survivors, respectively. Usual activities and mobility were the most commonly affected HRQOL dimension, with >30 % at 3 versus months and >20 % at 12-months of overall survivors reporting >= moderate problems. There was no difference between the groups in any of the EQ5D dimensions. Conclusions: Nearly one-in-two (47 %) of the intubated and non-intubated ICU survivors reported clinically significant psychological symptoms at 3 and 12-month follow-ups. Overall, more than 30 % at 3-months and over 20 % at 12-months of the survivors in both groups had moderate or worse problems with their usual activities and mobility. The presence of psychological symptoms and HRQOL impairments was similar between the groups. (c) 2023 The Authors. Published by Elsevier B.V. on behalf of College of Intensive Care Medicine of Australia and New Zealand. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

引用

页码：8 / 15

页数：8

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