Two-year efficacy, safety, and drug survival of dupilumab for atopic dermatitis: A real-world Canadian multicenter retrospective study

被引：22

作者：

Georgakopoulos, Jorge R. ^{[1
]}

Felfeli, Tina ^{[2
,3
]}

Drucker, Aaron M. ^{[1
,3
,4
]}

Jo, Christine E. ^{[5
]}

Piguet, Vincent ^{[1
,4
]}

Yeung, Jensen ^{[1
,6
,7
,8
]}

机构：

[1] Univ Toronto, Dept Med, Div Dermatol, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[2] Univ Toronto, Dept Ophthalmol & Vis Sci, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[3] Univ Toronto, Inst Hlth Policy Management & Evaluat, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[4] Womens Coll Hosp, Toronto, ON, Canada

[5] Univ Ottawa, Fac Med, Ottawa, ON, Canada

[6] Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada

[7] Prob Med Res Inc, Waterloo, ON, Canada

[8] Womens Coll Hosp, Dept Dermatol, 76 Grenville St,Fifth Floor, Toronto, ON M5S 1B2, Canada

来源：

JAAD INTERNATIONAL | 2021年 / 4卷

关键词：

adverse event; atopic dermatitis; drug survival; dupilumab; efficacy; safety;

D O I：

10.1016/j.jdin.2021.06.001

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

[No abstract available]

引用

页码：67 / 69

页数：3

共 4 条

[1] Dupilumab Provides Favorable Safety and Sustained Efficacy for up to 3 Years in an Open-Label Study of Adults with Moderate-to-Severe Atopic Dermatitis [J].

Beck, Lisa A. ;

Thaci, Diamant ;

Deleuran, Mette ;

Blauvelt, Andrew ;

Bissonnette, Robert ;

de Bruin-Weller, Marjolein ;

Hide, Michihiro ;

Sher, Lawrence ;

Hussain, Iftikhar ;

Chen, Zhen ;

Khokhar, Faisal A. ;

Beazley, Bethany ;

Ruddy, Marcella ;

Patel, Naimish ;

Graham, Neil M. H. ;

Ardeleanu, Marius ;

Shumel, Brad .

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2020, 21 (04) :567-577

[2] Long-term effectiveness and safety of treatment with dupilumab in patients with atopic dermatitis: Results of the TREAT NL (TREatment of ATopic eczema, the Netherlands) registry [J].

Bosma, Angela L. ;

de Wijs, Linde E. M. ;

Hof, Michel H. ;

van Nieuwenhuizen, Beau R. ;

Gerbens, Louise A. A. ;

Middelkamp-Hup, Maritza A. ;

Hijnen, DirkJan ;

Spuls, Phyllis, I .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2020, 83 (05) :1375-1384

[3] Dupilumab shows long-term safety and efficacy in patients with moderate to severe atopic dermatitis enrolled in a phase 3 open-label extension study [J].

Deleuran, Mette ;

Thaci, Diamant ;

Beck, Lisa A. ;

de Bruin-Weller, Marjolein ;

Blauvelt, Andrew ;

Forman, Seth ;

Bissonnette, Robert ;

Reich, Kristian ;

Soong, Weily ;

Hussain, Iftikhar ;

Foley, Peter ;

Hide, Michihiro ;

Bouaziz, Jean-David ;

Gelfand, Joel M. ;

Sher, Lawrence ;

Schuttelaar, Marie L. A. ;

Wang, Chen ;

Chen, Zhen ;

Akinlade, Bolanle ;

Gadkari, Abhijit ;

Eckert, Laurent ;

Davis, John D. ;

Rajadhyaksha, Manoj ;

Staudinger, Heribert ;

Graham, Neil M. H. ;

Pirozzi, Gianluca ;

Ardeleanu, Marius .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2020, 82 (02) :377-388

[4] Evaluation of long-term efficacy, safety, and reasons for discontinuation of dupilumab for moderate to severe atopic dermatitis in clinical practice: A retrospective cohort study [J].

Jo, Christine E. ;

Georgakopoulos, Jorge R. ;

Ladda, Matthew ;

Ighani, Arvin ;

Mufti, Asfandyar ;

Drucker, Aaron M. ;

Piguet, Vincent ;

Yeung, Jensen .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2020, 82 (06) :1530-1532

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