RT-PCR Result of SARS-CoV-2 Viral RNA in Cadavers and Viral Transmission Risk to Handlers

被引:1
作者
Panda, Bandita [1 ]
Singh, Nipa [2 ]
Singh, Gyanraj [3 ]
Patro, A. Raj K. [4 ]
Mohanty, Ambika P. [5 ]
Patnaik, Pradeep K. [6 ]
Misra, Ramnath [7 ]
机构
[1] Kalinga Inst Med Sci, Dept Res & Dev, Bhubaneswar, Odisha, India
[2] Kalinga Inst Med Sci, Dept Microbiol, Bhubaneswar, Odisha, India
[3] Jajati Keshari Med Coll & Hosp, Dept Anat, Jajpur, Odisha, India
[4] Kalinga Inst Med Sci, Dept Mol & Adv Diagnost, Bhubaneswar, Odisha, India
[5] Kalinga Inst Med Sci, Dept Gen Med, Bhubaneswar, Odisha, India
[6] Kalinga Inst Med Sci, Dept Hosp Management, Bhubaneswar, Odisha, India
[7] Kalinga Inst Med Sci, Dept Rheumatol Immunol & Res & Dev, Bhubaneswar, Odisha, India
关键词
Cadaver; Pandemic; RT-PCR; SARS-CoV-2; Transmission risk;
D O I
10.5005/jp-journals-10071-24730
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
During the onset of the pandemic, a common research question was asked by the hospital staff, and family members who were handling COVID19-infected cadavers, "does COVID-19-positive dead body harbor SARS-CoV-2 viral RNA?" Several research findings were reported but due to the lack of proper research findings, the question remained unanswered. The present study was planned to observe the virus transmission risk from cadavers to the handlers. A pilot study was conducted on 54 cadavers who died in COVID-ICU (SARS-CoV-2-positive diagnosed by RT-PCR) during 2021-2022. Skin swab sample from 54 dead bodies and 54 glove samples of handlers were taken within 1 hour of death for the RT-PCR test. Viability results from RT-PCR show that the infection risk was 50% in cadavers, whereas the transmission risk to handlers while handling was 7%, which is minimal. The SARS-CoV-2 viability was high in cases of those died after a long time of infection. Based on the RT-PCR result and data analysis the interpretation of the study was that the SARS-CoV-2 transmission risk from dead bodies to the handlers is minimal but the SARS-CoV-2 viability persists in the cadavers. This fact is helpful for the people who will conduct funeral activities, autopsy staff, and hospital staff handling dead bodies.
引用
收藏
页码:614 / 616
页数:3
相关论文
共 12 条
[1]  
[Anonymous], 2022, COVID-19 risks from handling the deceased
[2]  
Aquila Isabella, 2021, Med Leg J, V89, P40, DOI 10.1177/0025817220980601
[3]   COVID mortality in India: National survey data and health facility deaths [J].
Jha, Prabhat ;
Deshmukh, Yashwant ;
Tumbe, Chinmay ;
Suraweera, Wilson ;
Bhowmick, Aditi ;
Sharma, Sankalp ;
Novosad, Paul ;
Fu, Sze Hang ;
Newcombe, Leslie ;
Gelband, Hellen ;
Brown, Patrick .
SCIENCE, 2022, 375 (6581) :667-+
[4]   Basic Critical Care for Management of COVID-19 Patients: Position Paper of the Indian Society of Critical Care Medicine, Part II [J].
Juneja, Deven ;
Savio, Raymond D. ;
Srinivasan, Shrikanth ;
Pandit, Rahul A. ;
Ramasubban, Suresh ;
Reddy, Pavan K. ;
Singh, Manoj K. ;
Gopal, Palepu B. N. ;
Chaudhry, Dhruva ;
Govil, Deepak ;
Dixit, Subhal B. ;
Samavedam, Srinivas .
INDIAN JOURNAL OF CRITICAL CARE MEDICINE, 2020, 24 :S254-S262
[5]   Visitors in the Intensive Care Unit in the COVID Era [J].
Kapadia, Farhad Nahni ;
Pattanaik, Santiswaroop .
INDIAN JOURNAL OF CRITICAL CARE MEDICINE, 2022, 26 (03) :251-252
[6]   Detection and infectivity of SARS-CoV-2 in exhumated corpses [J].
Plenzig, S. ;
Holz, F. ;
Bojkova, D. ;
Kettner, M. ;
Cinatl, J. ;
Verhoff, M. A. ;
Birngruber, C. G. ;
Ciesek, S. ;
Rabenau, H. F. .
INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 2021, 135 (06) :2531-2536
[7]   Postmortem Stability of Ebola Virus [J].
Prescott, Joseph ;
Bushmaker, Trenton ;
Fischer, Robert ;
Miazgowicz, Kerri ;
Judson, Seth ;
Munster, Vincent J. .
EMERGING INFECTIOUS DISEASES, 2015, 21 (05) :856-859
[8]   Post-mortem persistence of SARS-CoV-2: a preliminary study [J].
Sablone, Sara ;
Solarino, Biagio ;
Ferorelli, Davide ;
Benevento, Marcello ;
Chironna, Maria ;
Loconsole, Daniela ;
Sallustio, Anna ;
Dell'Erba, Alessandro ;
Introna, Francesco .
FORENSIC SCIENCE MEDICINE AND PATHOLOGY, 2021, 17 (03) :403-410
[9]   SARS-CoV-2 antigen detection in deceased bodies: implications for infection prevention [J].
Sharma, Meenakshi ;
Kiro, Vandana Vijayeta ;
Srivastav, Sharad ;
Mansoori, Nasim ;
Lalwani, Parin ;
Lathwal, Amit ;
Agrawal, Richa ;
Soni, Kapil Dev ;
Madaan, Nirupam ;
Malhotra, Rajesh ;
Trikha, Anjan ;
Lalwani, Sanjeev ;
Mathur, Purva .
INDIAN JOURNAL OF MEDICAL RESEARCH, 2023, 158 (01) :33-39
[10]   Rate of shed of SARS COV-2 viral RNA from COVID-19 cadavers [J].
Sharma, Meenakshi ;
Brijwal, Megha ;
Chakraborty, Nabarun ;
Choudhary, Aashish ;
Kumar, Arbind ;
Srivastav, Sharad ;
Lalwani, Parin ;
Agrawal, Richa ;
Soni, Kapil Dev ;
Madaan, Nirupam ;
Malhotra, Rajesh ;
Mathur, Purva ;
Lalwani, Sanjeev ;
Dar, Lalit ;
Trikha, Anjan .
JOURNAL OF INFECTION AND PUBLIC HEALTH, 2022, 15 (12) :1486-1493