A Comprehensive on Synthesis and Antimicrobial Evaluation of Substituted-Arylideneamino-5-(5-Chlorobenzofuran-2-yl)-1, 2, 4-Triazole-3-Thiol Derivatives/Schiff Bases

被引：0

作者：

Rizwan, Muhammad ^{[1
]}

Noreen, Sobia ^{[2
]}

Asim, Sadia ^{[2
]}

Liaqat, Zohaib ^{[3
]}

Ibrahim, Hina ^{[4
]}

Talib, Rimsha ^{[1
]}

机构：

[1] Govt Coll Univ, Dept Chem, Faisalabad 38000, Pakistan

[2] Govt Coll Women Univ, Dept Chem, Faisalabad 38000, Pakistan

[3] Minhaj Univ Lahore, Dept Biochem, Lahore 54770, Punjab, Pakistan

[4] Univ Educ Lahore, Dept Chem, Faisalabad Campus, Lahore 38000, Pakistan

来源：

JOURNAL OF FLUORESCENCE | 2025年 / 35卷 / 06期

基金：

英国科研创新办公室;

关键词：

Schiff base; (R2C = NH) group; Biological activities; Efficient synthetic protocols; ONE-POT SYNTHESIS; SCHIFF-BASES; BIOLOGICAL-ACTIVITY; MANNICH-BASES; COMPLEXES; ANTIBACTERIAL; BENZOFURAN; IMINES; ISATIN; SALICYLALDEHYDE;

D O I：

10.1007/s10895-024-03817-3

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Schiff bases are well known and popular classes of organic compounds containing imine (R2C = NH) group that are widely used as catalysts and intermediates in numerous organic transformations. Schiff bases are medicinally very important because they exhibit antimicrobial like antibacterial, antiviral and anticancer activities. Benzofuran based Schiff bases have been found as interesting scaffolds for the synthesis and design of biologically active agents. Moreover, they possess a wide range of biological activities against fungal, bacterial, malarial, inflammatory and viral diseases. In this reviw, substituted-arylideneamino-5-(5-chlorobenzofuran-2-yl)-1,2,4-triazole-3-thiols have been synthesized by using efficient synthetic protocols. The synthesized derivatives are also evaluated against different bacterial strains.

引用

页码：3733 / 3761

页数：29

共 76 条

[1] Synthesis of Benzofuran-based Schiff bases as anti-diabetic compounds and their molecular docking studies [J].

Adalat, Bushra ;

Rahim, Fazal ;

Taha, Muhammad ;

Hayat, Shawkat ;

Iqbal, Naveed ;

Ali, Zarshad ;

Shah, Syed Adnan Ali ;

Wadood, Abdul ;

Rehman, Ashfaq Ur ;

Khan, Khalid Mohammed .

JOURNAL OF MOLECULAR STRUCTURE, 2022, 1265

[2] Novel Schiff base copper complexes of quinoline-2 carboxaldehyde as proteasome inhibitors in human prostate cancer cells [J].

Adsule, Shreelekha ;

Barve, Vivek ;

Chen, Di ;

Ahmed, Fakhara ;

Dou, Q. Ping ;

Padhye, Subhash ;

Sarkar, Fazlul H. .

JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (24) :7242-7246

[3]

Anwar S, 2020, Letters in Drug Design & Discovery, V17, P1579, DOI [10.2174/1570180817999200921112605, 10.2174/1570180817999200921112605, DOI 10.2174/1570180817999200921112605, https://doi.org/10.2174/1570180817999200921112605]

[4]

Ashraf MA, 2011, CHEMISTRY AND CHEMICAL PROCESS, P1

[5] A synergistic investigation of azo-thiazole derivatives incorporating thiazole moieties: a comprehensive exploration of their synthesis, characterization, computational insights, solvatochromism, and multimodal biological activity assessment [J].