Effect of Race and Insurance Status on Treatment and Outcomes in Diabetic Retinopathy: Analysis of 43 274 Eyes Using the IRIS Registry

被引:1
作者
Maturi, Jay [1 ,2 ]
Maturi, Vikas [2 ]
Scott, Adrienne W. [1 ,3 ]
Carson, Kathryn A. [1 ,4 ]
Ciulla, Thomas [2 ,5 ]
Maturi, Raj [2 ,5 ]
机构
[1] Johns Hopkins Univ, Sch Med, Baltimore, MD USA
[2] Midwest Eye Inst, Retina Serv, 10300 N Illinois St, Indianapolis, IN 46290 USA
[3] Johns Hopkins Univ, Sch Med, Wilmer Eye Inst, Retina Div, Baltimore, MD 21205 USA
[4] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA
[5] Indiana Univ, Sch Med, Dept Ophthalmol, Indianapolis, IN USA
关键词
diabetic retinopathy; antivascular endothelial growth factor; race; health equity; insurance; GROWTH-FACTOR THERAPY; MACULAR EDEMA; VISUAL-ACUITY; REAL-WORLD; INTRAVITREAL INJECTIONS; RACIAL-DIFFERENCES; DISPARITIES; RANIBIZUMAB; AFLIBERCEPT; BEVACIZUMAB;
D O I
10.1177/24741264231221607
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To examine disparities in visual acuity (VA) outcomes 1 year and 2 years after initiation of diabetic retinopathy (DR) or diabetic macular edema (DME) treatment in patients based on race/ethnicity and insurance status, accounting for disease severity. Methods: This retrospective analysis used the IRIS Registry and included DR patients older than 18 years with documented antivascular endothelial growth factor (anti-VEGF) treatment and VA data for at least 2 years. International Classification of Diseases, Tenth Revision, Clinical Modification codes were used to determine the severity of DR and DME presence. VA outcomes were assessed using multivariable linear regressions and anti-VEGF drug use by multivariable logistic regressions, with race and insurance status as independent variables. Main outcome measures comprised the mean VA change at 1 year and 2 years and percentage of patients treated with bevacizumab. Results: The study included 43 274 eyes. White patients presented with a higher mean VA and lower mean DR severity than Black patients and Hispanic patients. Multivariable logistic regression showed Hispanic patients were significantly more likely to be treated with bevacizumab than White patients across all insurance types, controlling for disease severity and VA. After 1 year, the letter improvement was 1.73, 1.33, and 1.13 in White patients, Black patients, and Hispanic patients, respectively. Multivariable linear regression suggested that across races, Medicaid-insured patients had significantly smaller gains in VA than privately insured patients. Conclusions: Race-based and insurance-based differences in 1-year and 2-year outcomes after anti-VEGF treatment for DR and anti-VEGF treatment patterns suggest a need to ensure earlier and more effective treatment of minority and underserved patients in the United States.
引用
收藏
页码:270 / 279
页数:10
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