Flare Phenomenon After 177Lu-DOTA-IBA Therapy in Bone Metastases of Lung Cancer

被引：4

作者：

Hua, Qingchu ^{[1
,2
,3
]}

Wang, Wei ^{[1
,2
,3
]}

Qu, Gengcuo ^{[1
,2
,3
]}

Pei, Wenjie ^{[1
,2
,3
]}

Chen, Yue ^{[1
,2
,3
]}

机构：

[1] Southwest Med Univ, Dept Nucl Med, Affiliated Hosp, 25 TaiPing St, Luzhou 646000, Sichuan, Peoples R China

[2] Nucl Med & Mol Imaging Key Lab Sichuan Prov, Luzhou, Sichuan, Peoples R China

[3] Southwest Med Univ, Inst Nucl Med, Luzhou, Sichuan, Peoples R China

来源：

CLINICAL NUCLEAR MEDICINE | 2024年 / 49卷 / 08期

关键词：

flare phenomenon; Lu-177; DOTA-IBA; bone metastases; lung cancer; bone pain;

D O I：

10.1097/RLU.0000000000005303

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The flare phenomenon is a transient increase in the number or intensity of lesions on bone scans after treatment, signifying curative effect. DOTA-ibandronic acid (DOTA-IBA) is a new prodrug that targets bone metastases and can be labeled with Lu-177. Here, we report the case of a 58-year-old woman with bone metastasis, in whom the flare phenomenon was observed after 4 cycles of Lu-177-DOTA-IBA treatment. No adverse effects were observed during the treatment and follow-up periods.

引用

页码：793 / 796

页数：4

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