Acute pancreatitis in Turkey: Results of a nationwide multicenter study

被引：2

作者：

Koksal, Aydin Seref ^{[1
,24
]}

Tozlu, Mukaddes ^{[1
]}

Sezgin, Orhan ^{[2
]}

Oguz, Dilek ^{[3
]}

Kalkan, Ismail Hakk ^{[4
]}

Altntas, Engin ^{[2
]}

Yaras, Serkan ^{[2
]}

Bilgic, Yilmaz ^{[5
]}

Yildirim, Abdullah Emre ^{[6
]}

Barutcu, Sezgin ^{[6
]}

Hakim, Gozde Dervis ^{[7
]}

Soytuerk, Muejde ^{[8
]}

Bengi, Goksel ^{[8
]}

Ozseker, Burak ^{[9
]}

Yurci, Alper ^{[10
]}

Koc, Deniz Oguetmen ^{[11
]}

Irak, Kader ^{[12
]}

Kasap, Elmas ^{[13
]}

Cindoruk, Mehmet ^{[14
]}

Oruc, Nevin ^{[15
]}

Unal, Nalan Guelsen ^{[15
]}

Sen, Ilker ^{[16
]}

Gokden, Yasemin ^{[17
]}

Saruc, Murat ^{[18
]}

Unal, Hakan ^{[18
]}

Eminler, Ahmet Tar ^{[1
]}

Toka, Bilal ^{[1
]}

Basir, Hakan ^{[2
]}

Saglam, Osman ^{[5
]}

Erguel, Bilal ^{[3
]}

Guel, Ozlem ^{[3
]}

Bueyuektorun, Ilker ^{[8
]}

Ozel, Mustafa ^{[10
]}

Sair, Uemit ^{[19
]}

Kosem, Gizem ^{[20
]}

Nedirli, Ferda ^{[21
]}

Tahtaci, Mustafa ^{[22
]}

Parlak, Erkan ^{[23
]}

机构：

[1] Sakarya Univ, Sch Med, Dept Gastroenterol, Serdivan, Turkiye

[2] Mersin Univ, Sch Med, Dept Gastroenterol, Mersin, Turkiye

[3] Kirikkale Univ, Sch Med, Dept Gastroenterol, Kirikkale, Turkiye

[4] TOBB Univ Econ & Technol, Dept Gastroenterol, Ankara, Turkiye

[5] Inonu Univ, Sch Med, Dept Gastroenterol, Malatya, Turkiye

[6] Gaziantep Univ, Sch Med, Dept Gastroenterol, Gaziantep, Turkiye

[7] Saglik Bilimleri Univ, Izmir Sch Med, Dept Gastroenterol, Istanbul, Turkiye

[8] Dokuz Eylul Univ, Sch Med, Dept Gastroenterol, Izmir, Turkiye

[9] Mugla Sitki Kocman Univ, Sch Med, Dept Gastroenterol, Kotekli, Turkiye

[10] Erciyes Univ, Sch Med, Dept Gastroenterol, Kayseri, Turkiye

[11] Diskapi Educ & Res Hosp, Dept Gastroenterol, Istanbul, Turkiye

[12] Saglik Bilimleri Univ, Basaksehir Cam & Sakura City Hosp, Dept Gastroenterol, Istanbul, Turkiye

[13] Manisa Celal Bayar Univ, Sch Med, Dept Gastroenterol, Manisa, Turkiye

[14] Gazi Univ, Sch Med, Dept Gastroenterol, Ankara, Turkiye

[15] Ege Univ, Sch Med, Dept Gastroenterol, Bornova, Turkiye

[16] Saglik Bilimleri Univ, Sisli Hamidiye Etfal Educ & Res Hosp, Dept Gastroenterol, Istanbul, Turkiye

[17] Saglik Bilimleri Univ, Dept Gastroenterol, Prof Dr Cemil Tascioglu City Hosoital, Istanbul, Turkiye

[18] Acibadem Mehmet Ali Aydinlar Univ, Sch Med, Dept Gastroenterol, Istanbul, Turkiye

[19] Saglik Bilimleri Univ, Gaziosmanpasa Educ & Res Hosp, Dept Internal Med, Istanbul, Turkiye

[20] Manisa Celal Bayar Univ, Sch Med, Dept Internal Med, Manisa, Turkiye

[21] Gazi Univ, Sch Med, Dept Internal Med, Ankara, Turkiye

[22] Ankara Yildirim Beyazit Univ, Dept Gastroenterol, Ankara, Turkiye

[23] Hacettepe Univ, Sch Med, Dept Gastroenterol, Ankara, Turkiye

[24] Kizilirmak mahallesi 1443 cadde,Akinci sitesi, TR-6510 Ankara, Turkiye

来源：

PANCREATOLOGY | 2024年 / 24卷 / 03期

关键词：

Pancreatitis; Etiology; Morphology; Mortality; Guideline; NECROTIZING PANCREATITIS; FLUID COLLECTIONS; GLOBAL INCIDENCE; MANAGEMENT; MORTALITY; CHOLECYSTECTOMY; INTERVENTION; GUIDELINE; NECROSIS; OUTCOMES;

D O I：

10.1016/j.pan.2023.10.005

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background: Acute pancreatitis (AP) is the most common gastrointestinal disease requiring hospitalization, with significant mortality and morbidity. We aimed to evaluate the clinical characteristics of AP and physicians ' compliance with international guidelines during its management. Methods: All patients with AP who were hospitalized at 17 tertiary centers in Turkey between April and October 2022 were evaluated in a prospective cohort study. Patients with insufficient data, COVID-19 and those aged below 18 years were excluded. The definitions were based on the 2012 revised Atlanta criteria. Results: The study included 2144 patients (median age:58, 52 % female). The most common etiologies were biliary (n = 1438, 67.1 %), idiopathic (n = 259, 12 %), hypertriglyceridemia (n = 128, 6 %) and alcohol (n = 90, 4.2 %). Disease severity was mild in 1567 (73.1 %), moderate in 521 (24.3 %), and severe in 58 (2.6 %) patients. Morphology was necrotizing in 4.7 % of the patients. The overall mortality rate was 1.6 %. PASS and BISAP had the highest accuracy in predicting severe pancreatitis on admission (AUC:0.85 and 0.81, respectively). CT was performed in 61 % of the patients, with the majority (90 %) being within 72 h after admission. Prophylactic NSAIDs were not administered in 44 % of the patients with post-ERCP pancreatitis (n = 86). Antibiotics were administered to 53.7 % of the patients, and 38 % of those received them prophylactically. Conclusions: This prospective study provides an extensive report on clinical characteristics, management and outcomes of AP in real -world practice. Mortality remains high in severe cases and physicians ' adherence to guidelines during management of the disease needs improvement in some aspects. (c) 2023 IAP and EPC. Published by Elsevier B.V. All rights reserved.

引用

页码：327 / 334

页数：8

共 43 条

[1] Endoscopic management of acute necrotizing pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) evidence-based multidisciplinary guidelines [J].